Experimental studies of arenaviral hemorrhagic fevers.
Experimental studies of arenaviral hemorrhagic fevers.
复制标题
沙粒病毒出血热的实验研究。
DOI:
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复制
发表时间:
1987
影响因子:
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通讯作者:
J. G. Oro
中科院分区:
文献类型:
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作者:
C. Peters;P. Jahrling;C. T. Liu;R. Kenyon;K. Mckee;J. G. Oro
Three arenaviruses, Lassa, Junin, and Machupo, regularly cause serious disease when they infect humans: Lassa fever, Argentine hemorrhagic fever (AHF), and Bolivian hemorrhagic fever (BHF), respectively. There is increasing acceptance that these and other human viral infections share sufficient, common, clinical and pathophysiological findings to refer to a viral hemorrhagic (HF) syndrome (Johnson and Peters 1985). This entity is characterized by fever, malaise, prostration, and evidence of diffuse vascular dysregulation and permeability changes. Hemorrhagic manifestations occur in many cases, usually in proportion to the gravity of the illness and the prognosis. The mechanisms underlying these clinical events probably vary depending on the infecting virus, but almost certainly share common themes (Peters and Johnson 1984). The biohazard of the causative viruses, the difficult logistics of clinical research in the regions where most HFs occur, and the limited international support for research on so-called “exotic” viruses have all been important barriers to progress in the field.
DOI:
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发表时间:
1983
期刊:
Federation proceedings
影响因子:
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作者:
Scott,WA;Rouzer,CA;Cohn,ZA
通讯作者:
Cohn,ZA
DOI:
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发表时间:
1986
期刊:
Journal of immunology (Baltimore, Md. : 1950)
影响因子:
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作者:
Ferreri,NR;Howland,WC;Spiegelberg,HL
通讯作者:
Spiegelberg,HL
DOI:
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发表时间:
1986
期刊:
Federation proceedings
影响因子:
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作者:
Lewis,RE;Granger,HJ
通讯作者:
Granger,HJ