Abnormalities of coherent motion processing in strabismic amblyopia: Visual-evoked potential measurements
Abnormalities of coherent motion processing in strabismic amblyopia: Visual-evoked potential measurements
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DOI：
10.1167/8.4.2
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发表时间：
2008-01-01
影响因子：
1.8
通讯作者：
Norcia, Anthony M.
中科院分区：
文献类型：
--
作者：
Hou, Chuan;Pettet, Mark W.;Norcia, Anthony M.
应用视觉诱发电位（VEP）对轻中度斜视性弱视患者与正常人的相干运动反应进行了比较。动态随机点运动图，交替在0.83赫兹之间的全球连贯（左-右）和不连贯（随机）的运动状态引起的反应。调谐曲线在。对于空间位移3.1至27.9弧分（1.6至9.3度/秒），全局运动更新速率的第一谐波（0.83 Hz）和点更新速率的第一谐波（20 Hz）。响应锁定的局部方向矢量的全球组织的变化是一个倒U形的位移/速度的功能，在正常视力的观察者和斜视患者的同胞的眼睛，而弱视眼的调谐功能转移到更大的位移/更高的速度。点更新率的反应在患者的双眼中的幅度降低并且在时间上改变。这一结果与斜视性弱视的局部和整体运动加工缺陷相一致。
Coherent motion responses of patients with mild to moderate strabismic amblyopia were compared to those of normals using visual-evoked potentials (VEPs). Responses were elicited by dynamic random-dot kinematograms that alternated at 0.83 Hz between globally coherent (left-right) and incoherent (random) motion states. Tuning curves were measured at the. rst harmonic of the global motion update rate (0.83 Hz) and at the first harmonic of the dot update rate (20 Hz) for spatial displacements 3.1 to 27.9 arcmin (1.6 to 9.3 deg/s). Responses locked to the changes in the global organization of the local direction vectors were an inverted U-shaped function of displacement/speed in the normal-vision observers and in the fellow eyes of the strabismus patients while the tuning function of the amblyopic eyes was shifted to larger displacements/higher speeds. Responses at the dot update rate were reduced in amplitude and altered in timing in both eyes of the patients. The results are consistent with both local and global deficits in motion processing in strabismic amblyopia.