LONG-TERM OBSERVATIONS OF VERTEBRAL FRACTURES IN SPINAL OSTEOPOROTICS
LONG-TERM OBSERVATIONS OF VERTEBRAL FRACTURES IN SPINAL OSTEOPOROTICS
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DOI：
10.1007/bf02555920
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发表时间：
1990-10-01
影响因子：
4.2
通讯作者：
KASAMA, F
中科院分区：
文献类型：
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作者：
ITOI, E;SAKURAI, M;KASAMA, F
通过对21例脊柱骨质疏松症患者的长期观察（平均7年），研究了椎体骨折数量和分布的变化。楔形骨折呈双相分布，以胸椎中段和胸腰椎为高峰。双凹型骨折主要发生在腰椎。这些分布模式在观察期间没有改变。双凹型骨折发生率增高，楔形骨折发生率降低，塌陷骨折发生率保持不变。骨折数量的变化分为三种类型；递增型、平稳型、不变型。随着骨质疏松的进展，增高型被认为转变为平台型，这可能是脊柱骨质疏松的终末阶段。相比之下，未改变型与其他两种类型不同，因为脊柱骨密度增加，尿钙减少，这表明脊柱骨质疏松症在钙代谢方面是不均匀的。
The changes in the number and distributions of vertebral fractures were studied from the long-term observations (average 7 years) of 21 spinal osteoporotic patients. Distribution of wedge fractures was biphasic with peak frequencies at the midthoracic and thoracolumbar spine. Biconcave fractures occurred predominantly in the lumbar spine. These patterns of distribution did not change during the period of observation. The rate of biconcave fracture increased, the rate of wedge fracture decreased, and that of collapse remained the constant in follow-up. The changes in the number of fractures were divided into three types; increasing, plateau, and unchanged type. With the advance of osteoporosis, the increasing type was considered to change into the plateau type, which is probably the terminal stage of spinal osteoporosis. The unchanged type, in contrast, was distinct from the other two types because of increased spinal bone mineral density and decreased urinary calcium, which suggests that spinal osteoporosis is heterogeneous with regard to calcium metabolism.