Characterization of diffraction-enhanced imaging contrast in breast cancer.
Characterization of diffraction-enhanced imaging contrast in breast cancer.
复制标题
乳腺癌衍射增强成像对比度的表征。
DOI:
10.1088/0031-9155/54/10/019
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发表时间:
2009
影响因子:
3.5
通讯作者:
Zhong,Z
中科院分区:
文献类型:
--
作者:
Kao,T;Connor,D;Dilmanian,FA;Faulconer,L;Liu,T;Parham,C;Pisano,ED;Zhong,Z
Diffraction-enhanced imaging (DEI) is a new x-ray imaging modality that has been shown to enhance contrast between normal and cancerous breast tissues. In this study, diffraction-enhanced imaging in computed tomography (DEI-CT) mode was used to quantitatively characterize the refraction contrasts of the organized structures associated with invasive human breast cancer. Using a high-sensitivity Si (3 3 3) reflection, the individual features of breast cancer, including masses, calcifications and spiculations, were observed. DEI-CT yields 14, 5 and 7 times higher CT numbers and 10, 9 and 6 times higher signal-to-noise ratios (SNR) for masses, calcifications and spiculations, respectively, as compared to conventional CT of the same specimen performed using the same detector, x-ray energy and dose. Furthermore, DEI-CT at ten times lower dose yields better SNR than conventional CT. In light of the recent development of a compact DEI prototype using an x-ray tube as its source, these results, acquired at a clinically relevant x-ray energy for which a pre-clinical DEI prototype currently exists, suggest the potential of clinical implementation of mammography with DEI-CT to provide high-contrast, high-resolution images of breast cancer (Parham 2006 PhD Dissertation University of North Carolina at Chapel Hill).
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影响因子:
--
作者:
John T. Thompson;S. D. Bustros;R. Michels;T. Rice
通讯作者:
T. Rice
DOI:
--
发表时间:
1989
期刊:
A M A Archives of Ophthalmology
影响因子:
--
作者:
George A. Williams;Gary W. Abrams;W. Mieler
通讯作者:
W. Mieler
DOI:
--
发表时间:
1981
期刊:
Retina
影响因子:
--
作者:
R. Michels
通讯作者:
R. Michels
DOI:
--
发表时间:
1987
期刊:
American journal of ophthalmology-glaucoma
影响因子:
--
作者:
Gary W. Abrams;George A. Williams
通讯作者:
George A. Williams
影响因子:
4.2
作者:
LEWIS, H;ABRAMS, GW;WILLIAMS, GA
通讯作者:
WILLIAMS, GA