Association of birthplace and occupational exposures with chronic bronchitis in US Hispanics/Latinos, 2008-2011.
Association of birthplace and occupational exposures with chronic bronchitis in US Hispanics/Latinos, 2008-2011.
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2008-2011 年美国西班牙裔/拉丁裔出生地和职业暴露与慢性支气管炎的关联。
DOI：
10.1136/oemed-2019-106081
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发表时间：
2020
影响因子：
4.9
通讯作者：
Diaz,Alejandro
中科院分区：
文献类型：
--
作者：
Kim,Victor;Wang,Wei;Mannino,David;Diaz,Alejandro
目的在美国，慢性支气管炎（CB）是常见的，并与大量的发病率和死亡率。关于西班牙裔/拉丁裔人口中CB的数据-一个庞大的，多样化的美国少数民族-是稀缺的。我们的目的是测试CB的患病率是否在西班牙裔/拉丁美洲人的遗产中有所不同，并确定CB的危险因素，包括职业暴露，在这一population.MethodsWe分析了来自西班牙裔社区健康研究/拉丁美洲人研究的数据，这是一项以美国人口为基础的18-74岁参与者概率样本（n= 16415）包括那些与墨西哥，波多黎各，多米尼加，古巴，中美洲和南美洲的遗产。分析中纳入了已完成呼吸问卷和有效肺量测定数据的参与者（n= 13259）。CB、出生地、遗产、职业暴露和其他风险因素基于标准化问卷。CB的患病率估计使用调查Logistic回归条件边际analysis.ResultsThe估计（平均值（95%CI））的CB的总体调整患病率为12.1%（9.3至15.6），与一个大的变化，在遗传。多米尼加遗产的流行率比南美遗产高五倍。美国出生的受试者的校正患病率高于非美国出生的受试者（16.8%（12.5至22.1）vs 11.0%（8.5至14.10）; p=0.022）。与非暴露的参与者相比，那些暴露于清洁或消毒解决方案有较高的调整后的患病率CB（12.6%（9.1至17.1）与11.8%（9.2至15.1）; P=0.024）。CB在美国出生的参与者和接触清洁和消毒溶液的参与者中更为普遍。
ObjectivesIn the US, chronic bronchitis (CB) is common and is associated with substantial morbidity and mortality. Data on CB in the Hispanic/Latino population—a large, diverse US minority—are scarce. We aimed to test whether the prevalence of CB varies across Hispanic/Latino heritages and to identify CB risk factors, including occupational exposures, in this population.MethodsWe analysed data from the Hispanic Community Health Study/Study of Latinos, a US population-based probability sample of participants aged 18–74 years (n=16 415) including those with Mexican, Puerto Rican, Dominican, Cuban, Central American and South American heritages. Participants who had a completed respiratory questionnaire and valid spirometric data were included in the analysis (n=13 259). CB, place of birth, heritage, occupational exposures and other risk factors were based on standardised questionnaires. The prevalence of CB was estimated using survey logistic regression-conditional marginal analysis.ResultsThe estimated (mean (95% CI)) overall adjusted prevalence of CB was 12.1% (9.3 to 15.6), with a large variation across heritages. Dominican heritage had a fivefold higher prevalence than South American heritage. US-born participants had a higher adjusted prevalence than their non-US-born counterparts (16.8% (12.5 to 22.1) vs 11.0% (8.5 to 14.10); p=0.022). Compared with non-exposed participants, those exposed to cleaning or disinfecting solutions had a higher adjusted prevalence of CB (12.6% (9.1 to 17.1) vs 11.8% (9.2 to 15.1); p=0.024).ConclusionsThe prevalence of CB was higher among Dominicans than other Hispanic/Latino heritages. CB was more prevalent among US-born participants and those exposed to cleaning and disinfecting solutions.