Synthesis and structure revision of tyroscherin, a growth inhibitor of IGF-1-dependent tumor cells
Synthesis and structure revision of tyroscherin, a growth inhibitor of IGF-1-dependent tumor cells
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DOI:
10.1016/j.tetlet.2008.09.141
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发表时间:
2008-12-01
影响因子:
1.8
通讯作者:
Kitahara, Takeshi
中科院分区:
文献类型:
--
作者:
Katsuta, Ryo;Shibata, Chie;Kitahara, Takeshi
Synthesis of the Proposed structure of tyroscherin, a growth inhibitor of IGF-1-dependent cancer cells, was succeeded by one-pot Julia Coupling. However, spectral data of the synthetic compound were not identical with those of natural tyroscherin. The stereochemistry of tyroscherin was revised to be 2S,3R,8R,10R by syntheses of stereoisomers. (c) 2008 Elsevier Ltd. All rights reserved.