POST-TRAUMATIC AMNESIA IN CLOSED HEAD INJURY
POST-TRAUMATIC AMNESIA IN CLOSED HEAD INJURY
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DOI：
10.1001/archneur.1961.00450130006002
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发表时间：
1961-01-01
影响因子：
--
通讯作者：
SMITH, A
中科院分区：
文献类型：
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作者：
RUSSELL, WR;SMITH, A
通过对1766例闭合性颅脑损伤患者的临床特征与5个不同时间间隔的PTA发生率的相关性分析，探讨创伤后遗忘症（PTA）作为严重程度指标的意义。PTA应用的局限性被定义为从总人口中排除例外情况。根据选择差异将剩余种群分为4组，论证了影响PTA敏感性和可靠性的因素。精选的代表性结果显示，在所有4个人群中，PTA较长的大多数临床特征的发生率全身性增加，也反映了人群差异。年龄与PTA的关系分析表明，PTA持续时间随年龄的增长而增加，在固定的PTA时间间隔内，临床特征的发生率随年龄的增长而增加。体征和症状随着PTA持续时间的增加而系统地增加，与年龄相关的关系相同；临床特征不随PTA持续时间增加，也不受年龄的影响。体征和症状与PTA增加和年龄呈系统性正相关（包括结构改变的迹象），被武断地定义为“主要是有机的”。其他不受PTA增加和年龄影响的（主要是情绪性的）被武断地定义为“非器质性”或“心因性”。在大约100种不同的体征和症状中，对于没有局灶性损伤迹象的病例，如凹陷性骨折或颅内出血，PTA是最敏感和最可靠的严重程度指标。考虑到患者的年龄，PTA持续时间的重要性进一步确定。本文讨论了PTA在闭合性颅脑损伤诊断和分类中的应用。
The significance of post-traumatic amnesia (PTA) as an index of severity was studied in 1766 cases of closed head injury by correlating the incidence of clinical features with 5 different intervals of PTA. Limitations of the application of PTA were defined in the exclusion of exceptional cases from the total population. Factors influencing the Schsitivity and reliability of PTA were demonstrated by division of the total remaining population into 4 groups on the basis of differences in selection. Selected repreSchtative results, which showed systemic increases in incidence of most clinical features with longer PTA in all 4 populations, also reflected population differences. Analyses of the relationships of age and PTA showed that the duration of PTA increases with age and, that within fixed PTA intervals, the incidence of clinical features rises with age. Signs and symptoms that systematically increased with duration of PTA showed the same relationship when correlated with age; clinical features that did not increase with duration of PTA were also not influenced by age. Signs and symptoms showing systematic positive correlations with increasing PTA and age (which included signs of structural alterations) were arbitrarily defined as "primarily organic." Others that were unaffected by increasing PTA and age (which were largely emotional in character) were arbitrarily defined as "nonorganic" or psychogenic." Of approximately 100 different signs and symptoms, PTA emerged as the most Schsitive and reliable index of severity for cases without signs of focal damage, such as depressed fracture or intracranial hemorrhage. The significance of the duration of PTA is further defined by taking the age of the patient into account. Practical and theoretical implications for prevailing diagnostic and classification methods of closed head injury and other applications of PTA are discussed.