EFFECTS OF AGE, CIGARETTE-SMOKING, AND OTHER FACTORS ON FERTILITY - FINDINGS IN A LARGE PROSPECTIVE-STUDY
EFFECTS OF AGE, CIGARETTE-SMOKING, AND OTHER FACTORS ON FERTILITY - FINDINGS IN A LARGE PROSPECTIVE-STUDY
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DOI：
10.1136/bmj.290.6483.1697
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发表时间：
1985-01-01
影响因子：
105.7
通讯作者：
YEATES, D
中科院分区：
文献类型：
--
作者：
HOWE, G;WESTHOFF, C;YEATES, D
在参加英国牛津计划生育协会避孕研究的 17,032 名女性中，有 4104 名女性停止使用避孕方法来计划怀孕，总共 6199 次。通过测量生育孩子所需的时间来评估各种因素对这些妇女生育能力的影响。在未生育过的女性和已生育过的女性中，停止避孕的年龄与生育能力之间都观察到明显的负相关关系，但在未生育过的女性中，这种影响要大得多。最重要的发现是随着每天吸烟数量的增加，生育率下降的趋势是一致且非常显着的。据估计，在停止避孕5年后，每天吸烟超过20支的吸烟者中，有10.7%的人未生育，而非吸烟者中只有5.4%的人仍未生育。生育率与社会阶层、结婚年龄和妇科病史之间存在一定的相关性，但体重、身高和Quetelet指数没有显着影响。
Of 17,032 women taking part in the Oxford Family Planning Association [UK] contraceptive study, 4104 stopped using a birth control method to plan a pregnancy on a total of 6199 occasions. The influence of various factors on fertility in these women was assessed by measuring the time taken to give birth to a child. An appreciable inverse relation was observed between age at stopping contraception and fertility both in nulliparous and parous women, but the effect was much greater in the nulliparous women. The most important finding was a consistent and highly significant trend of decreasing fertility with increasing numbers of cigarettes smoked per day; it was estimated that 5 yr after stopping contraception 10.7% of smokers smoking more than 20 cigarettes a day, but only 5.4% of non-smokers, remained undelivered. Some relation was found between fertility and social class, age at marriage and a history of gynecological disease, but weight, height and Quetelet''s index were without noticeable effect.