ALCOHOL-INDUCED HYPERTENSION
ALCOHOL-INDUCED HYPERTENSION
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酒精引起的高血压
DOI：
10.1016/s0140-6736(81)90995-8
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发表时间：
1980
期刊：
影响因子：
--
通讯作者：
A. Paton
中科院分区：
文献类型：
--
作者：
J. B. Saunders;D. G. Beevers;A. Paton
对132例日均饮酒量超过80g的酒精中毒患者在饮酒时、戒酒期间和戒酒一段时间后进行血压测量。51.5%的患者在发病时血压超过140/90。在过去三个月中，血压和平均每日酒精摄入量之间以及血压水平和酒精戒断症状的严重程度之间存在显著的相关性。血压与肝组织学损害程度无关，但与血清γ-谷氨酰转移酶活性和平均红细胞体积相关。大多数患者的血压在戒毒后降至正常，而那些继续戒毒的患者至少保持了一年的血压。然而，重新开始饮酒的人血压上升。过量饮酒是高血压的一个重要原因，但人们对此认识不足，尽管确切的机制尚不清楚，但如果能说服患者戒酒，治疗是简单而有效的。
Blood pressures of 132 alcoholic patients whose mean daily alcohol consumption exceeded 80 g were measured while drinking, during detoxification from alcohol, and after a period of abstinence. At the time of presentation blood pressure exceeded 140/90 in 51·5% of patients. There was a significant correlation between blood pressure and mean daily alcohol intake over the previous three months and also between the level of blood pressure and the severity of alcohol-withdrawal symptoms. There was no relation between blood pressure and degree of histological liver damage, but a correlation was found with serum γ-glutamyl-transferase activity and with mean corpuscular volume. In most patients blood pressure fell to normal after detoxification, and remained so for at least a year in those who continued to abstain. However, blood pressure rose in those who started drinking again. Excessive alcohol consumption is an important and insufficiently recognised cause of hypertension and, although the exact mechanism is unknown, treatment is simple and effective if patients can be persuaded to abstain.