Puberty-affecting synthetic analogs of urinary chemosignals in the house mouse, Mus domesticus
Puberty-affecting synthetic analogs of urinary chemosignals in the house mouse, Mus domesticus
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影响青春期的家鼠泌尿化学信号的合成类似物
DOI：
10.1016/0031-9384(89)90270-9
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发表时间：
1989
影响因子：
2.9
通讯作者：
M. Novotny
中科院分区：
文献类型：
--
作者：
B. Jemioło;F. Andreolini;T. Xie;D. Wiesler;M. Novotny
在之前的一项研究中确定了雌性小鼠尿液中内分泌学和社会性依赖的挥发性成分，测试了它们加速年轻雌性动物青春期和延长发情期的能力。在55-75%的暴露女性中，几种挥发酮将青春期提前了大约三天，并延长了阴道角化期。高浓度的这些物质能够覆盖已知的延缓青春期的化学信号。挥发性环烯醇醚也能有效地延长发情期，但不能加速青春期。
Endocrinologically- and socially-dependent volatile constituents of female mouse urine, identified in a previous study, were tested for their capability to accelerate puberty and extend the estrous period in young females. Several volatile ketones advanced puberty by approximately three days and extended the period of vaginal cornification in 55–75% of exposed females. High concentrations of these substances were capable of overriding the known puberty-delaying chemosignals. Volatile cyclic enol ethers were also effective in extending estrus, but not puberty acceleration.