Minimum alveolar concentrations (MAC) of halothane, enflurane, and isoflurane in ferrets.
Minimum alveolar concentrations (MAC) of halothane, enflurane, and isoflurane in ferrets.
复制标题
雪貂中氟烷、安氟烷和异氟烷的最低肺泡浓度 (MAC)。
DOI：
10.1097/00000542-198805000-00018
复制
发表时间：
1988
期刊：
影响因子：
8.8
通讯作者：
Housmans,PR
中科院分区：
文献类型：
--
作者：
Murat,I;Housmans,PR
在恒温（37℃）条件下，测定了成年雄性雪貂在受控通风条件下异氟烷、安氟烷和氟烷的最低肺泡浓度（MAC）。异氟烷（n= 8）、安氟烷（n= 8）和氟烷（n= 8）在37℃时的平均（+/-SD） MAC值分别为1.52+/-0.10%、1.99+/-0.18%和1.01+/-0.10%。在70% N2O的存在下，氟烷的MAC降低了26%。在29.9+/-0.2℃时，卤代烷的平均MAC值（0.85+/-0.11%）比37℃时的MAC值低16%。卤代麻醉药的相对效力与报道的大型动物和人类的相对效力相同。
The minimum alveolar concentrations (MAC) of isoflurane, enflurane, and halothane were determined in adult male ferrets during controlled ventilation at normothermia (37 degrees C). Mean (+/-SD) MAC values for isoflurane (n= 8), enflurane (n= 8), and halothane (n= 8) at 37 degrees C were 1.52+/-0.10%, 1.99+/-0.18%, and 1.01+/-0.10%, respectively. Halothane MAC was reduced by 26% in the presence of 70% N2O. At 29.9+/-0.2 degrees C, the mean MAC value of halothane (0.85+/-0.11%) was 16% less than MAC at 37 degrees C. The relative potencies of the halogenated anesthetics are of the same order as those reported for large animals and for humans.