Investigating temporal lobe contribution to confrontation naming using MRI quantitative volumetrics
Investigating temporal lobe contribution to confrontation naming using MRI quantitative volumetrics
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DOI：
10.1017/s135561770505054x
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发表时间：
2005-07-01
影响因子：
2.6
通讯作者：
Hermann, B
中科院分区：
文献类型：
--
作者：
Seidenberg, M;Geary, E;Hermann, B
对抗命名能力需要不同的认知操作和分布式神经网络的完整性。先前的研究表明，左颞叶区域在命名能力中起着关键作用，但对不同颞叶区域的相对作用却不太一致。在本文中，我们使用定量磁共振容积测量，以调查海马和海马外颞叶（分段灰色和白色物质）体积的相对贡献，以对抗命名性能在53例颞叶癫痫患者。结果显示：（1）左颞叶体积与命名能力的关系比右颞叶体积更强;（2）左颞叶白色物质体积和左海马体积对自发命名能力都有显著的独特方差贡献;（3）左颞叶白色物质体积而不是左海马体积对再认命名能力有预测作用。
Confrontation naming ability entails the operation of distinct cognitive operations and the integrity of a distributed neural network. Previous research has indicated a critical role for the left temporal lobe region in naming ability, but there is less agreement about the relative role of distinct temporal lobe regions. In the current paper, we used quantitative MR volumetrics to investigate the relative contribution of the hippocampus and extrahippocampal temporal lobe (segmented gray and white matter) volumes to confrontation naming performance in 53 patients with temporal lobe epilepsy. Findings showed (1) a stronger relationship for left temporal lobe volume than right temporal lobe volume in predicting naming performance; (2) both left temporal lobe white matter volume and left hippocampus volume contributed a significant amount of unique variance to spontaneous naming performance; and (3) left temporal lobe white matter volume but not left hippocampus volume predicted recognition naming performance.