Studies of S-But-3-ynyl and gem-Dimethyl S-But-3-ynyl Thioglycoside Donors in Gold-Catalyzed Glycosylations
Studies of S-But-3-ynyl and gem-Dimethyl S-But-3-ynyl Thioglycoside Donors in Gold-Catalyzed Glycosylations
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DOI：
10.1080/07328303.2013.831433
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发表时间：
2013-07-24
影响因子：
1
通讯作者：
Zhu, Jianglong
中科院分区：
文献类型：
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作者：
Adhikari, Surya;Li, Xiaohua;Zhu, Jianglong
研究了以S-丁基-3-炔基和宝石-二甲基S-丁基-3-炔基硫代糖苷为供体的金催化糖基化反应，合成了各种复杂的寡糖。研究发现，2，2-二甲基S-3-炔基硫代糖苷供体比S-3-炔基硫代糖苷供体具有更高的反应活性，并以相对较高的产率得到糖苷产品。
Gold-catalyzed glycosylation using S-but-3-ynyl and gem-dimethyl S-but-3-ynyl thioglycoside donors has been investigated for the synthesis of various types of complex oligosaccharides. It was found that 2,2-dimethyl S-but-3-ynyl thioglycoside donors are more reactive than their S-but-3-ynyl thioglycoside counterparts and gave the glycoside products in relatively higher yields.