Influence of light and dark on the free amino acid pattern of the developing chick retina.
Influence of light and dark on the free amino acid pattern of the developing chick retina.
复制标题
光和暗对发育中的小鸡视网膜游离氨基酸模式的影响。
DOI：
10.1016/0006-8993(73)90567-2
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发表时间：
1973
期刊：
影响因子：
2.9
通讯作者：
P. Mandel
中科院分区：
文献类型：
--
作者：
H. Pasantes‐morales;J. Klethi;M. Ledig;P. Mandel
本文研究了鸡视网膜发育过程中游离氨基酸的变化。除GABA、谷氨酰胺、甘氨酸和赖氨酸外，其它氨基酸含量在孵化17 ~ 20 d呈下降趋势，在孵化20 ~ 1 d呈上升趋势。成虫在孵化后30天内达到水平。牛磺酸浓度在孵化后的视网膜中增加，与出生后的大脑和其他器官中的这种氨基酸的减少形成对比。在完全黑暗或连续光照下孵育鸡蛋不影响氨基酸水平的正常变化。在孵化后的第一天，GABA含量显着增加，观察到在视网膜中的光暴露的小鸡;牛磺酸水平增加了90%以上，在黑暗中饲养的动物。牛磺酸作为一种突触递质或调制器在视网膜中的可能作用进行了讨论。
Changes in free amino acids of the developing chicken retina were studied. All amino acid levels except GABA, glutamine, glycine and lysine decreased between the 17th and the 20th incubation days, then increased between the 20th incubation day and the 1st day after hatching. Adult levels were attained within 30 days of hatching. Taurine concentrations increased in the retina after hatching, contrasting with the post-natal decrease of this amino acid in brain and other organs.The influence of light and darkness on the developing free amino acid pattern in retina was examined. Incubation of eggs in total darkness or in continuous illumination did not affect the normal changes in amino acid levels. During the first days after hatching a significant increase in GABA content was observed in the retina of light-exposed chicks; taurine levels were increased by more than 90% in the dark-reared animals. A possible role of taurine as a synaptic transmitter or modulator in retina is discussed.