The Use of Propensity Scores in Mediation Analysis
The Use of Propensity Scores in Mediation Analysis
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DOI：
10.1080/00273171.2011.576624
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发表时间：
2011-01-01
影响因子：
3.8
通讯作者：
Vinokur, Amiram D.
中科院分区：
文献类型：
--
作者：
Jo, Booil;Stuart, Elizabeth A.;Vinokur, Amiram D.
中介分析使用假设的中介变量的测量来测试治疗如何对结果产生影响的理论，并通过确定最有效的治疗成分来改进后续治疗。当前大多数中介分析方法依赖于未经测试的分布和函数形式假设来得出有效结论，特别是关于中介变量和结果变量之间的关系。倾向评分方法提供了另一种选择，即使用倾向评分来比较治疗组和对照组中的个体，如果他们被分配到相同的治疗条件，这些个体将具有相同的中介值。本文介绍了倾向得分加权在调解中的使用，重点是解释基本假设。倾向得分有可能为中介分析提供替代的估计程序，并提供标准中介分析的替代假设。这些方法通过使用求职干预研究 (JOBS II) 的数据来研究干预措施的中介效应，以提高掌握感以减少抑郁。我们发现，对于那些在治疗条件下掌握感有所改善的个体来说，治疗效果显着，但对于那些在治疗下不会改善掌握感的个体则没有效果。
Mediation analysis uses measures of hypothesized mediating variables to test theory for how a treatment achieves effects on outcomes and to improve subsequent treatments by identifying the most efficient treatment components. Most current mediation analysis methods rely on untested distributional and functional form assumptions for valid conclusions, especially regarding the relation between the mediator and outcome variables. Propensity score methods offer an alternative whereby the propensity score is used to compare individuals in the treatment and control groups who would have had the same value of the mediator had they been assigned to the same treatment condition. This article describes the use of propensity score weighting for mediation with a focus on explicating the underlying assumptions. Propensity scores have the potential to offer an alternative estimation procedure for mediation analysis with alternative assumptions from those of standard mediation analysis. The methods are illustrated investigating the mediational effects of an intervention to improve sense of mastery to reduce depression using data from the Job Search Intervention Study (JOBS II). We find significant treatment effects for those individuals who would have improved sense of mastery when in the treatment condition but no effects for those who would not have improved sense of mastery under treatment.