Studies concerning the behavior of actinomycin in solution.

Studies concerning the behavior of actinomycin in solution.
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关于放线菌素在溶液中行为的研究。

DOI:
10.1021/bi00845a028
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发表时间:
1968
期刊:
影响因子:
2.9
通讯作者:
W. Müller
W. Müller
中科院分区:
生物学3区
文献类型:
--
作者:
D. Crothers;S. Sabol;D. I. Ratner;W. Müller

文献摘要

被引文献

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唐纳德·M·克罗瑟斯。F Steven L.Sabol,J David I.Ratner,{和Werner Müler摘要:用平衡离心法和旋光分散法研究了放线菌素的二聚化和构象变化。在放线菌素的水溶液中形成一种特殊的二聚体,其二聚常数约为103m-1。二聚反应的热和熵较大且为负值。光致旋光色散谱
Donald M. Crothers. f Steven L. Sabol, J David I. Ratner,{and Werner Müller abstract: Dimerization and conformational change of actinomycin are investigated by equilibrium centrifugation and opticalrotatory dispersion. A specific dimer forms in aqueous solutions of actinomycin, with a dimerization constant of roughly 103 m-1. The heat and entropy of dimerization are relatively large and negative. The optical rotatory dispersion spectrum of actino-