Association analysis of mitochondrial DNA polymorphisms with oocyte number in pigs
Association analysis of mitochondrial DNA polymorphisms with oocyte number in pigs
复制标题
猪线粒体DNA多态性与卵母细胞数量的关联分析
DOI：
10.1071/rd18219
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发表时间：
2019-03-01
影响因子：
1.9
通讯作者：
Zhao, Xingbo
中科院分区：
文献类型：
--
作者：
Liu, Hao;Shi, Wenshu;Zhao, Xingbo
在猪中，线粒体 (mt) DNA 多态性与经济性状之间的相关性已在猪品种之间和内部得到广泛报道。在生育力研究中，卵巢内卵母细胞的数量与窝产仔数高度相关。然而，线粒体多态性对猪卵母细胞数量的影响仍不清楚。本研究收集了181个猪卵巢，分析卵母细胞数量与mtDNA多态性之间的关系。商品猪品种不同卵巢的卵母细胞数量存在显着差异，范围为2.7x10(5)至1.3x10(6)。线粒体 D 环测序发现 53 个多态性位点。关联分析显示，13 个变异与卵母细胞数量相关（P
In pigs, correlations between mitochondrial (mt) DNA polymorphisms and economic traits have been widely reported across and within swine breeds. In fecundity studies, the number of oocytes within ovaries was highly correlated with litter size. However, the effect of mitochondrial polymorphisms on porcine oocyte number remained unclear. In this study, 181 porcine ovaries were collected to analyse the relationship between oocyte number and mtDNA polymorphisms. There were considerable differences in oocyte numbers among different ovaries from commercial pig breeds, ranging from 2.7x10(5) to 1.3x10(6). Mitochondrial D-loop sequencing discovered 53 polymorphic sites. Association analysis revealed that 13 variations were associated with the number of oocytes (P