Sharpened cortical tuning and enhanced cortico-cortical communication contribute to the long-term neural mechanisms of visual motion perceptual learning
Sharpened cortical tuning and enhanced cortico-cortical communication contribute to the long-term neural mechanisms of visual motion perceptual learning
复制标题
敏锐的皮质调节和增强的皮质-皮质沟通有助于视觉运动感知学习的长期神经机制
DOI：
10.1016/j.neuroimage.2015.04.041
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发表时间：
2015-07-15
期刊：
影响因子：
5.7
通讯作者：
Fang, Fang
中科院分区：
文献类型：
--
作者：
Chen, Nihong;Bi, Taiyong;Fang, Fang
关于调节知觉学习的神经可塑性是发生在大脑的感觉阶段还是决策阶段，一直存在很多争论。为了研究这一点，我们训练人类受试者进行视觉运动方向辨别任务。在训练前、训练后和训练后两周分别测量行为表现和BOLD信号。在受试者行为持续改善的同时，V3A的神经选择性和V3A到IPS（顶叶内沟，运动决策区）的有效连通性在训练方向上持续增加。此外，这种改善可以很好地解释为选择性和连通性增加的线性组合。这些发现表明，运动知觉学习的长期神经机制是通过在感觉处理阶段强化皮层对训练刺激的调谐，以及优化大脑中感觉和决策区域之间的连接来实现的。(C) 2015爱思唯尔公司版权所有。
Much has been debated about whether the neural plasticity mediating perceptual learning takes place at the sensory or decision-making stage in the brain. To investigate this, we trained human subjects in a visual motion direction discrimination task. Behavioral performance and BOLD signals were measured before, immediately after, and two weeks after training. Parallel to subjects' long-lasting behavioral improvement, the neural selectivity in V3A and the effective connectivity from V3A to IPS (intraparietal sulcus, a motion decisionmaking area) exhibited a persistent increase for the trained direction. Moreover, the improvement was well explained by a linear combination of the selectivity and connectivity increases. These findings suggest that the long-term neural mechanisms of motion perceptual learning are implemented by sharpening cortical tuning to trained stimuli at the sensory processing stage, as well as by optimizing the connections between sensory and decision-making areas in the brain. (C) 2015 Elsevier Inc. All rights reserved.