Technical considerations for dominant frequency analysis
Technical considerations for dominant frequency analysis
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DOI：
10.1111/j.1540-8167.2007.00810.x
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发表时间：
2007-07-01
影响因子：
2.7
通讯作者：
Goldberger, Jeffrey J.
中科院分区：
文献类型：
--
作者：
Ng, Jason;Kadish, Alan H.;Goldberger, Jeffrey J.
引言：心房电描记图的主频（DF）分析已用于表征房颤（AF）。本研究的目的是探讨技术问题，可能会影响估计的局部激活率在AF使用DF analysis.Methods和结果：心外膜心房电图记录在AF从10只狗被用来评估单极与双极记录，双极电极间距，postrecording处理，远场心室去极化，心室模板减法，DF分析和信号持续时间的影响。模拟心电图用于评价远场心室除极和信噪比的影响。将DF与通过手动标记获得的激活率进行比较，并评价DF的再现性。发现双极电描记图优于单极电描记图。预处理是双极信号的必要步骤，但也有助于单极记录的分析。心室远场去极化显著影响DF。心室模板减影有助于在具有最小和显著心室分量的信号中进行DF分析。可靠的DF测量需要2秒以上的记录持续时间。信噪比低于13分贝也会影响DF，特别是信号具有显着的幅度和频率variation.Conclusions：各种因素影响DF分析。DF分析的正确解释需要仔细评估AF信号和强大的处理技术。
Introduction: Dominant frequency (DF) analysis of atrial electrograms has been used to characterize atrial fibrillation (AF). The aim of this study was to explore technical issues that may affect the estimation of local activation rate during AF using DF analysis.Methods and Results: Epicardial atrial electrograms recorded during AF from 10 dogs were used to evaluate the effects of unipolar versus bipolar recordings, bipolar electrode spacing, postrecording processing, far field ventricular depolarizations, ventricular template subtraction, and signal duration on DF analysis. Simulated electrograms were used to evaluate the effect of far field ventricular depolarizations and signal-to-noise ratio. DFs were compared with activation rates obtained by manual marking and the reproducibility of the DFs was evaluated. Bipolar electrograms were found to be preferable to unipolar electrograms. Preprocessing was a necessary step for bipolar signals, but also aided analysis of unipolar recordings. Ventricular far field depolarizations significantly affected DFs. Ventricular template subtraction helped DF analysis in signals with both minimal and significant ventricular components. A recording duration above 2 seconds was required for reliable DF measurements. Signal-to-noise ratios below 13 dB could also affect DF, particularly for signals with significant amplitude and frequency variation.Conclusions: Various factors affect DF analysis. Proper interpretation of DF analysis requires careful evaluation of the AF signals and robust processing techniques.