Endocrine characteristics of the menstrual cycle in the Assamese monkey (Macaca assamensis).

Endocrine characteristics of the menstrual cycle in the Assamese monkey (Macaca assamensis).
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阿萨姆猴(Macaca assamensis)月经周期的内分泌特征。

DOI:
10.1095/biolreprod23.3.522
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发表时间:
1980
影响因子:
3.6
通讯作者:
Ferin,M
Ferin,M
中科院分区:
生物学2区
文献类型:
--
作者:
Wehrenberg,WB;Dyrenfurth,I;Ferin,M

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对16只恒河猴月经周期的内分泌特征进行了测定。平均周期为32±2天,分为16±1天的卵泡期和16±1天的黄体期。黄体生成素和卵泡刺激素的浓度在整个周期中几乎保持不变,但在周期中期,两种促性腺激素都会激增。促黄体生成激素(FSH)由3±1升至9±1μg/ml,卵泡刺激素(FSH)由3±1升至9±1μg/ml,卵泡期雌激素由2 75±75升至43 2±89 pg/ml,黄体期孕酮由不到0 5 ng/ml升至2~4 ng/ml。尽管动物之间存在差异,但这些激素的浓度和模式与其他物种猕猴的报告相似。这些结果表明,阿萨姆斯猴可以作为研究灵长类生殖生理的合适模型。
The endocrine characteristics of the menstrual cycle were determined in 16 Assamese monkeys (Macaca assamensis). Average cycle length was 32 ± 2 (± SEM) days which was divided into a 16 ± 1 day follicular phase and a 16 ± 1 day luteal phase. LH and FSH concentrations were fairly constant throughout the cycle except at midcycle when both gonadotropins surged. At this time LH concentrations increased from 4 ± 2 to 17 ± 4μg/ml (mean ± SEM) and FSH from 3 ± 1 to 9 ± 1μg/ml. Estrogens also increased at midcydle from 275 ± 75 to 432 ± 89 pg/ml. Progesterone rose from less than 0.5 ng/ml during the follicular phase to between 2 and 4 ng/ml during the luteal phase. Although there was variation between animals, the concentrations and patterns of these hormones were similar to those reported for other species of macaques. These results suggest that the Assamese monkey can serve as an appropriate model for the study of primate reproductive physiology.