Thermoregulation in the life cycle of nematodes
Thermoregulation in the life cycle of nematodes
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DOI：
10.1016/j.ijpara.2006.02.006
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发表时间：
2006-05-31
影响因子：
4
通讯作者：
Devaney, Eileen
中科院分区：
文献类型：
--
作者：
Devaney, Eileen
An unanswered question in the biology of many parasites is the mechanism by which environmental (or external) and intrinsic signals are integrated to determine the switch from one developmental stage to the next. This is particularly pertinent for nematode parasites, many of which have a free-living stage in the environment prior to infection of the mammalian host, or for parasites such as filarial nematodes, which utilise an insect vector for transmission. The environmental changes experienced by a parasite upon infection of a mammalian host are extremely complex and poorly understood. However, the ability of a parasite to sense its new environment must be intrinsically linked to its developmental programme, as progression of the life cycle is dependent upon the infection event. In this review, the relationship between temperature and development in filarial nematodes and in the free-living species Caenorhabditis elegans is summarised, with a focus on the role of heat shock factor and heat shock protein 90 in the nematode life cycle. (c) 2006 Australian Society for Parasitology Inc Published by Elsevier Ltd. All rights reserved.
