Poincare plot of heart rate variability allows quantitative display of parasympathetic nervous activity in humans
Poincare plot of heart rate variability allows quantitative display of parasympathetic nervous activity in humans
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DOI：
10.1042/cs0910201
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发表时间：
1996-08-01
期刊：
影响因子：
6
通讯作者：
Tonkin, AM
中科院分区：
文献类型：
--
作者：
Kamen, PW;Krum, H;Tonkin, AM
1.心率变异性可以通过时域概括统计量和频域参数来测量，近年来，包括Poincare图在内的定性方法被用于心率变异性的评估，本研究的目的是验证一种新的方法，使用传统的统计技术定量分析Poincare图.在相对较短的时间内测量心跳间心率变异性（10-20分钟），12名年龄在20 - 40岁之间的健康受试者（平均30+/-7岁）（i）仰卧位休息，（ii）头高位倾斜（交感神经激活，副交感神经系统活动消退），（iii）静脉内输注阿托品（副交感神经系统活动消退），和（iv）低剂量经皮东莨菪碱过夜给药后（副交感神经系统增强）。Poincare图的“宽度”由SD Δ R-R（连续R-R间期之间的差异）量化，在静息时测定（中位数48.9，四分位数显著四分位数范围13.7 ms，P
1. Time domain summary statistics and frequency domain parameters can be used to measure heart rate variability, More recently, qualitative methods including the Poincare plot have been used to evaluate heart rate variability, The aim of this study was to validate a novel method of quantitative analysis of the Poincare plot using conventional statistical techniques.2. Beat-to-beat heart rate variability was measured over a relatively short period of time (10-20 min) in 12 healthy subjects aged between 20 and 40 years (mean 30+/-7 years) during (i) supine rest, (ii) head-up tilt (sympathetic activation, parasympathetic nervous system activity withdrawal), (iii) intravenous infusion of atropine (parasympathetic nervous system activity withdrawal), and (iv) after overnight administration of low-dose transdermal scopolamine (parasympathetic nervous system augmentation).3. The 'width' of the Poincare plot, as quantified by SD delta R-R (the difference between successive R-R intervals), was determined at rest (median 48.9, quartile significantly quartile range 13.7 ms, P