Simulation study of a D-shape PET scanner for improved sensitivity and reduced cost in whole-body imaging
Simulation study of a D-shape PET scanner for improved sensitivity and reduced cost in whole-body imaging
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D 形 PET 扫描仪的模拟研究，以提高全身成像的灵敏度并降低成本
DOI：
10.1088/1361-6560/aa6853
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发表时间：
2017
影响因子：
3.5
通讯作者：
Hideaki Tashima and Taiga Yamaya
中科院分区：
文献类型：
--
作者：
Abdella M Ahmed;Hideaki Tashima and Taiga Yamaya
正电子发射断层摄影（PET）扫描仪的灵敏度和成像性能的提高是研究的重点。传统上，可以通过增加轴向方向上的检测器环的数量（但成本高）或减小扫描仪的直径（缺点是减少了患者的空间并由于视差而降低了空间分辨率）来增加灵敏度。在这项研究中，我们提出了一种PET扫描仪与截断环和阵列的探测器，可以安排在一条直线下的床。我们称这个系统为“D-PET”，因为它在逆时针方向旋转90度时类似于字母“D”。基本的设计思想是切割病人床下未使用的空间;这个区域通常不用于临床诊断。我们进行了蒙特卡罗模拟的D-PET扫描仪，并比较其性能与圆柱形PET扫描仪。扫描器由4层相互作用深度探测器构成，该探测器由尺寸为2.85× 2.85× 5 mm 3的16× 16× 4 LYSO晶体阵列组成。结果表明，D-PET的灵敏度和峰值NECR分别提高了30%和18%。与圆柱形PET相比，D-PET在整个视场的重建图像中具有低噪声。这些都是在为患者保留足够空间的同时实现的，并且对空间分辨率也没有严重影响。此外，与圆柱形PET扫描仪相比，D-PET扫描仪的探测器数量（因此成本）减少了12%。
Much research effort is being made to increase the sensitivity and improve the imaging performance of positron emission tomography (PET) scanners. Conventionally, sensitivity can be increased by increasing the number of detector rings in the axial direction (but at high cost) or reducing the diameter of the scanner (with the disadvantages of reducing the space for patients and degrading the spatial resolution due to the parallax error). In this study, we proposed a PET scanner with a truncated ring and an array of detectors that can be arranged in a straight line below the bed. We called this system'D-PET'as it resembles the letter'D'when it is rotated by 90 in the counterclockwise direction. The basic design idea was to cut the unused space under the patient's bed; this area is usually not in use in clinical diagnosis. We conducted Monte Carlo simulations of the D-PET scanner and compared its performance with a cylindrical PET scanner. The scanners were constructed from 4-layer depth-of-interaction detectors which consisted of a 16× 16× 4 LYSO crystal array with dimensions of 2.85× 2.85× 5 mm 3. The results showed that the D-PET had an increase in sensitivity and peak-NECR of 30% and 18%, respectively. The D-PET had low noise in the reconstructed images throughout the field-of-view compared to the cylindrical PET. These were achieved while keeping sufficient space for the patient, and also without a severe effect on the spatial resolution. Furthermore, the number of detectors (and hence the cost) of the D-PET scanner was reduced by 12% compared to the cylindrical PET scanner.