Dissolution behavior of plasma-sprayed hydroxyapatite coatings
Dissolution behavior of plasma-sprayed hydroxyapatite coatings
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DOI：
10.1023/a:1008901512273
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发表时间：
2000-12-01
影响因子：
3.7
通讯作者：
Marquis, PM
中科院分区：
文献类型：
--
作者：
Fazan, F;Marquis, PM
等离子喷涂羟基磷灰石涂层的长期稳定性受到涂层在体内条件下溶解行为的影响。等离子喷涂产生的相的混合物，本研究的重点是如何平衡的相影响的涂层在双蒸馏去离子水和三-缓冲溶液中的体外溶解行为。监测双蒸馏去离子水中的pH变化，同时在37 ℃和5%CO2气氛下将tris缓冲溶液的pH值保持在7.25。分别用紫外可见分光光度计和原子吸收分光光度计测定释放的磷酸盐和钙离子。晶体和表面拓扑结构的变化进行了研究。结果表明，涂层的溶解行为取决于几个因素。磷酸根离子的释放速率被发现显着增加的三-缓冲溶液相比，去离子水，表明电解质成分的存在影响涂层的溶解行为。Tris缓冲溶液中的Ca/P比约为3。涂层的结晶度水平的增加显著降低了溶解速率，因此，磷酸根离子的释放量。结晶度的百分比越高，涂层在体外条件下的稳定性越高。(C)2000 Kluwer Academic Publishers.
The long-term stability of plasma-sprayed hydroxyapatite coatings is influenced by the dissolution behavior of the coating in in vivo conditions. Plasma-spraying generates a mixture of phases and this study has focused on how the balance of phases affects the in vitro dissolution behavior of the coatings in double distilled-deionized water and in tris-buffer solutions. The pH changes in double distilled-deionized water were monitored, whilst the pH value was maintained at 7.25 for the tris-buffer solution at 37 degreesC with 5% CO2 atmosphere. The phosphate and calcium ions released were measured using UV-Visible Spectrophotometer and Atomic Absorption Spectroscopy respectively. Changes in crystal and surface topology were also studied. The results indicate that the dissolution behavior of the coatings depends on several factors. The rate of release of phosphate ions was found to increase significantly for the tris-buffer solution compared to the deionized water, indicating that the presence of electrolyte constituents affects the dissolution behavior of the coatings. The Ca/P ratio in the tris-buffer solution is approximately three. Increases in the level of crystallinity of the coatings significantly decreased the dissolution rate and hence, the amount of phosphate ions released. The higher the percentage of crystallinity, the higher the stability of the coating under in vitro conditions. (C) 2000 Kluwer Academic Publishers.