Comprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma With Minor Glandular Component
Comprehensive Analysis of Oncogenic Mutations in Lung Squamous Cell Carcinoma With Minor Glandular Component
复制标题
伴有微小腺体成分的肺鳞状细胞癌致癌突变的综合分析
DOI：
10.1378/chest.12-2679
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发表时间：
2014-03-01
期刊：
影响因子：
9.6
通讯作者：
Chen, Haiquan
中科院分区：
文献类型：
--
作者：
Pan, Yunjian;Wang, Rui;Chen, Haiquan
背景：EGFR、ALK、BRAF、HER2、DDR2、RET 和 AKT1 等致癌基因的突变定义了对靶向治疗具有潜在敏感性的非小细胞肺癌 (NSCLC) 亚群。目前，微小鳞状细胞癌的突变谱、患病率和临床病理特征（
Background: The mutations in oncogenic genes, such as EGFR, ALK, BRAF, HER2, DDR2, RET, and AKT1, defined subsets of non-small cell lung cancers (NSCLCs) with potential sensitivity to targeted therapies. At present, the mutational spectrum, prevalence, and clinicopathologic characteristics in squamous cell carcinomas with minor (