Introduction of taurine into polymer brush grafted onto porous hollow-fiber membrane
Introduction of taurine into polymer brush grafted onto porous hollow-fiber membrane
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DOI：
10.1016/j.memsci.2005.04.025
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发表时间：
2005-11
影响因子：
9.5
通讯作者：
K. Miyoshi;Kyoichi Saito;Tomoyuki Shiraishi;T. Sugo
中科院分区：
文献类型：
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作者：
K. Miyoshi;Kyoichi Saito;Tomoyuki Shiraishi;T. Sugo
以含环氧基的单体甲基丙烯酸缩水甘油酯为单体，通过辐射引发接枝聚合反应，在环氧基团中加入牛磺酸和亚硫酸钠，制备了两种含磺酸基团的中空纤维膜。剩余的环氧基团被定量地水解成二醇基团。牛磺酸引入的中空纤维膜(TAU-diol纤维)与鸡蛋溶菌酶(HEL)在大约6层膜中结合，同时将其通量维持在起始中空纤维膜的60%，而引入亚硫酸钠的中空纤维膜(SS-diol纤维)的通量可以忽略不计。这种差异可以用牛磺酸的两性基团，即氨基和磺酸基团抑制接枝链的延伸这一事实来解释。HEL吸附通过缠绕接枝链而导致接枝链收缩，从而增加了通量。TAU(25)-二醇纤维对HEL的平衡结合容量为130 mg/g，其中25表示牛磺酸加到环氧基上的摩尔转化率。此外，在渗透模式下HEL在TAU-diol纤维上的高通量吸附是因为HEL对接枝链上的磺酸基团的扩散传质阻力可以忽略不计，这是由于牛磺酸加入到环氧基上。与磺酸基团相邻的二醇基团阻止了HEL在TAU-二醇纤维上的非选择性吸附。
Two types of sulfonic-acid-group-containing porous hollow-fiber membranes were prepared by radiation-induced graft polymerization of an epoxy-group-containing monomer, glycidyl methacrylate, and the subsequent addition of taurine (NH2CH2CH2SO3H) and sodium sulfite (Na2SO3) to some epoxy groups. The remaining epoxy groups were quantitatively hydrolyzed into a diol group. The taurine-introduced porous hollow-fiber membrane (TAU-diol fiber) bound hen egg lysozyme (HEL) in approximately six multilayers while maintaining its flux at 60% of the starting porous hollow-fiber membrane, whereas the sodium sulfite-introduced porous hollow-fiber membrane (SS-diol fiber) showed a negligible flux. This difference can be explained by the fact that the amphoteric moieties, i.e., amino and sulfonic acid groups of taurine, suppress the extension of the graft chain. HEL adsorption caused the graft chain to shrink by tangling the graft chain and thereby increasing flux. The equilibrium binding capacity of the TAU(25)-diol fiber for HEL, where the number 25 denotes the molar conversion of the addition of taurine to the epoxy group, was 130mg/g of the TAU-diol fiber. Furthermore, a high-throughput adsorption of HEL onto the TAU-diol fiber in the permeation mode was demonstrated because of the negligible diffusional mass-transfer resistance of HEL to the sulfonic acid group of the graft chain originating from the addition of taurine to the epoxy group. The diol group adjacent to the sulfonic acid group prevented the nonselective adsorption of HEL onto the TAU-diol fiber.