A versatile platform for surface modification of microfluidic droplets.
A versatile platform for surface modification of microfluidic droplets.
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DOI：
10.1039/c7lc00079k
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发表时间：
2017-02-14
期刊：
影响因子：
6.1
通讯作者：
Leong KW
中科院分区：
文献类型：
--
作者：
Li M;Jiang W;Chen Z;Suryaprakash S;Lv S;Tang Z;Chen X;Leong KW
为了推进乳液液滴技术，我们合成了Pluronic F127的功能衍生物，它们可以同时作为表面活性剂和液滴表面装饰的反应位点。胺-、羧基-、N-羟基琥珀酰亚胺酯-、马来酰亚胺-和生物素-封端的Pluronic F127允许通过静电吸附、共价缀合或位点特异性抗生物素蛋白-生物素相互作用将配体固定在单乳液或双乳液液滴上。液滴表面修饰：用于微流体乳液表面修饰的方法，可精确控制液滴表面特性。
To advance emulsion droplet technology, we synthesize functional derivatives of Pluronic F127 that can simultaneously act as surfactants and as reactive sites for droplet surface decoration. The amine-, carboxyl-, N-hydroxysuccinimide ester-, maleimide- and biotin-terminated Pluronic F127 allows ligand immobilization on single-emulsion or double-emulsion droplets via electrostatic adsorption, covalent conjugation or site-specific avidin-biotin interaction. Droplet surface decoration: Method for surface modification of microfluidic emulsions, with precise control over droplet surface properties.