Fasting respiratory quotient as a predictor of long-term weight changes in non-obese women
Fasting respiratory quotient as a predictor of long-term weight changes in non-obese women
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DOI：
10.1159/000079556
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发表时间：
2004-01-01
影响因子：
3.9
通讯作者：
Pasanisi, F
中科院分区：
文献类型：
--
作者：
Marra, M;Scalfi, L;Pasanisi, F
背景/目的：确定代谢和环境的预测过剩的身体脂肪仍然远远没有实现。本研究的目的是评估非肥胖女性的呼吸商是否是6年随访期后体重变化的预测因子。方法：43名非肥胖健康女性参与了本研究。他们的基线一般特征为：年龄40.5 ± 12.8岁;身高159 ± 7 cm;体重61.8 ± 10.1 kg，体重指数（BMI）24.4 ± 3.8 kg/m2。在基线时，基础代谢率和呼吸商通过间接量热法测定，而体重和BMI在第一次观察和3年和6年随访后记录。结果：首次观察时，基础代谢率为5，360 +/- 713 kJ/d，呼吸商为0.850 +/- 0.052。6年后，体重变化等于1.4 +/- 4.5 kg，基线呼吸商是体重或BMI变化与基线BMI的显著预测因子（p < 0.05）。结论：这项随访研究证实，高呼吸商（在自由饮食中测量）易导致体重增加，特别是在基线呼吸商最高的女性中（高于该变量分布的第90百分位数）。版权所有（C）2004 S. Karger AG，巴塞尔。
Background/Aims: The identification of metabolic and environmental predictors of excess body fat is still far from being achieved. The aim of this study was to evaluate whether respiratory quotient in non-obese women is a predictor of body weight changes after a 6-year follow-up period. Methods: Forty-three non-obese healthy women participated in the study. Their baseline general characteristics were: age 40.5 +/- 12.8 years; height 159 +/- 7 cm; weight 61.8 +/- 10.1 kg, and body mass index (BMI) 24.4 +/- 3.8 kg/m(2). At baseline basal metabolic rate and respiratory quotient were determined by indirect calorimetry, while weight and BMI were recorded at the first observation and after the 3- and 6-year follow-ups. Results: At the first observation basal metabolic rate was 5,360 +/- 713 kJ/day and respiratory quotient 0.850 +/- 0.052. After 6 years, with weight changes equal to 1.4 +/- 4.5 kg, baseline respiratory quotient was a significant predictor (p < 0.05) of changes in body weight or BMI together with baseline BMI. Conclusions: This follow-up study confirms that a high respiratory quotient (measured on free diet) predisposes to weight gain, especially in women with the highest baseline respiratory quotient (above the 90th percentile of the distribution for this variable). Copyright (C) 2004 S. Karger AG, Basel.