Study of photon migration with various source-detector separations in near-infrared spectroscopic brain imaging based on three-dimensional Monte Carlo modeling
Study of photon migration with various source-detector separations in near-infrared spectroscopic brain imaging based on three-dimensional Monte Carlo modeling
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DOI：
10.1364/opex.13.008339
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发表时间：
2005-10-17
期刊：
影响因子：
3.8
通讯作者：
Hsieh, JC
中科院分区：
文献类型：
--
作者：
Lee, CK;Sun, CW;Hsieh, JC
我们基于三维蒙特卡罗程序模拟了不同源-探测器分离方式下的光子迁移。仿真中引入了全脑MRI结构图像，建立的脑模型比以往的研究更准确。脑模型由头皮、头骨、脑脊液层、灰质和白质组成。我们演示了不同源-探测器分离情况下的动态传播电影。通过标记每个光子可以到达的最深层来获得大脑模型每一层的多次后向散射强度。还揭示了吸收目标对大脑皮层的影响。(C)2005年美国光学学会。
We have simulated the photon migration with various source-detector separations based on a three-dimensional Monte Carlo code. The whole brain MRI structure images are introduced in the simulation, and the brain model is more accurate then the previous studies. The brain model consists of scalp, skull, CSF layer, gray matter, and white matter. We demonstrate dynamic propagating movies under different source-detector separations. The multiple backscattered intensity from every layer of the brain model is obtained by marking the deepest layer which every photon can reach. Also the influences of an absorption target on brain cortex are revealed. (c) 2005 Optical Society of America.