Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.
Continuous lymphoid cell lines with characteristics of B cells (bone-marrow-derived), lacking the Epstein-Barr virus genome and derived from three human lymphomas.
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具有 B 细胞（骨髓来源）特征的连续淋巴细胞系，缺乏 Epstein-Barr 病毒基因组，源自三种人类淋巴瘤。
DOI：
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发表时间：
1974
影响因子：
11.1
通讯作者：
C. Sundström
中科院分区：
文献类型：
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作者：
G. Klein;T. Lindahl;M. Jondal;W. Leibold;J. Menezes;K. Nilsson;C. Sundström
通过核酸杂交（互补 RNA.DNA）和 Epstein-Barr 病毒确定的核抗原测试，测试了三种特殊细胞系是否存在 Epstein-Barr 病毒基因组。两条线来自瑞典淋巴瘤病例，另一条线来自非洲伯基特样淋巴瘤活检，其 Epstein-Barr 病毒 DNA 和病毒确定的核抗原呈阴性。所有三个品系显然都缺乏病毒基因组。三个细胞系中的两个明显具有 B 细胞（骨髓来源）的特征。
Three exceptional cell lines have been tested for the presence of the Epstein-Barr virus genome by nucleic acid hybridization (complementary RNA.DNA) and Epstein-Barr virus-determined nuclear antigen tests. Two lines were derived from Swedish lymphoma cases and one from an African Burkitt-like lymphoma biopsy that was negative for Epstein-Barr virus DNA and the virus-determined nuclear antigen. All three lines apparently lacked the viral genome. Two of the three lines clearly had characteristics of B-cells (bone-marrow-derived).