Sex-specific fitness effects of nutrient intake on reproduction and lifespan
Sex-specific fitness effects of nutrient intake on reproduction and lifespan
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DOI：
10.1016/j.cub.2008.06.059
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发表时间：
2008-07-22
期刊：
影响因子：
9.2
通讯作者：
Brooks, Robert C.
中科院分区：
文献类型：
--
作者：
Maklakov, Alexel A.;Simpson, Stephen J.;Brooks, Robert C.
饮食会影响寿命和繁殖 [1-9]，因此我们预测，不同性别的不同繁殖策略会导致营养对健康和寿命产生性别特异性影响 [6, 10]，并有利于男性和女性不同的营养摄入模式。然而，男性和女性共享大部分基因组，位点内性冲突可能会阻碍性别特异性饮食优化。我们发现，在田间蟋蟀中，高碳水化合物低蛋白饮食下，雄性和雌性的寿命都最大化，但雄性和雌性的终生繁殖性能在营养摄入景观的明显不同部分得到最大化。如果有选择的话，蟋蟀表现出性别特异性的饮食偏好，朝着提高繁殖性能的方向发展，但这种性别二态性偏好是不完整的，两性都偏离了终生繁殖的最佳饮食。因此，由于饮食选择的共同生物学特性，性别达到特定性别饮食最佳状态的能力受到限制。我们的数据表明，迄今为止，性别特异性选择未能完全解决饮食优化方面的座内性别冲突。这种冲突可能是将营养和生殖与寿命和衰老联系起来的重要因素。
Diet affects both lifespan and reproduction [1-9], leading to the prediction that the contrasting reproductive strategies of the sexes should result in sex-specific effects of nutrition on fitness and longevity [6, 10] and favor different patterns of nutrient intake in males and females. However, males and females share most of their genome and intralocus sexual conflict may prevent sex-specific diet optimization. We show that both male and female longevity were maximized on a high-carbohydrate low-protein diet in field crickets Teleogryllus commodus, but male and female lifetime reproductive performances were maximized in markedly different parts of the nutrient intake landscape. Given a choice, crickets exhibited sex-specific dietary preference in the direction that increases reproductive performance, but this sexual dimorphism in preference was incomplete, with both sexes displaced from the optimum diet for lifetime reproduction. Sexes are, therefore, constrained in their ability to reach their sex-specific dietary optima by the shared biology of diet choice. Our data suggest that sex-specific selection has thus far failed fully to resolve intralocus sexual conflict over diet optimization. Such conflict may be an important factor linking nutrition and reproduction to lifespan and aging.