Micro-Computed Tomography Assessment of Human Alveolar Bone: Bone Density and Three-Dimensional Micro-Architecture
Micro-Computed Tomography Assessment of Human Alveolar Bone: Bone Density and Three-Dimensional Micro-Architecture
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DOI：
10.1111/cid.12109
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发表时间：
2015-04-01
影响因子：
3.6
通讯作者：
Henkin, Jeffrey
中科院分区：
文献类型：
--
作者：
Kim, Yoon Jeong;Henkin, Jeffrey
背景：微型计算机断层扫描(Micro-CT)是评估和保护人体尸检标本和小型活体动物骨密度和质量相关信息的一种有价值的手段。目的：本研究的目的是利用微型CT测量人身体牙槽骨的骨密度。评价骨密度与骨小梁三维微结构的相关性。材料和方法：取34例人身体颌骨标本。每个标本均采用显微CT扫描，分辨率为10.5m。测量感兴趣体积内的骨体积分数(BV/TV)和骨密度(BMD)。评价骨小梁的三维微结构。上颌骨和下颌骨的所有参数均进行比较。采用Spearman‘s Rho对影响骨密度和三维微结构的变量进行非参数相关分析。
Background:Micro-computed tomography (micro-CT) is a valuable means to evaluate and secure information related to bone density and quality in human necropsy samples and small live animals.Purpose:The aim of this study was to assess the bone density of the alveolar jaw bones in human cadaver, using micro-CT. The correlation between bone density and three-dimensional micro architecture of trabecular bone was evaluated.Materials and Methods:Thirty-four human cadaver jaw bone specimens were harvested. Each specimen was scanned with micro-CT at resolution of 10.5m. The bone volume fraction (BV/TV) and the bone mineral density (BMD) value within a volume of interest were measured. The three-dimensional micro architecture of trabecular bone was assessed. All the parameters in the maxilla and the mandible were subject to comparison. The variables for the bone density and the three-dimensional micro architecture were analyzed for nonparametric correlation using Spearman's rho at the significance level of p