Concise review: stem cells as an emerging platform for antibody therapy of cancer.
Concise review: stem cells as an emerging platform for antibody therapy of cancer.
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DOI:
10.1002/stem.513
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发表时间:
2010-11
期刊:
影响因子:
5.2
通讯作者:
Aboody, Karen S.
中科院分区:
文献类型:
--
作者:
Frank, Richard T.;Najbauer, Joseph;Aboody, Karen S.
关键词:
Monoclonal antibodies are important tools for cancer therapy, however, three factors limit their effectiveness: toxicity, poor tumor penetration, and inability to cross the blood-brain barrier. This review discusses the emerging field of stem cell-mediated antibody delivery and how this approach may improve antibody therapy of cancer by overcoming these obstacles. STEM CELLS 2010;28:2084–2087
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