A direct comparison between ERP and fMRI measurements of food-related inhibitory control: Implications for BMI status and dietary intake
A direct comparison between ERP and fMRI measurements of food-related inhibitory control: Implications for BMI status and dietary intake
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DOI：
10.1016/j.neuroimage.2017.11.008
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发表时间：
2018-02-01
期刊：
影响因子：
5.7
通讯作者：
Larson, Michael J.
中科院分区：
文献类型：
--
作者：
Carbine, Kaylie A.;Duraccio, Kara M.;Larson, Michael J.
肥胖和保持健康饮食对身心健康有重要影响。可能影响饮食和肥胖的一个因素是抑制控制。我们测试了N2和P3振幅，反映抑制控制的事件相关电位（ERP）组件，以及与抑制控制相关的大脑区域中的功能性磁共振成像（fMRI）活动如何在BMI状态下对高热量和低热量食物刺激不同。我们还评估了食物相关的抑制控制和实验室和每日食物摄入量的神经指标之间的关系。54名个体（17名正常体重; 18名超重; 19名肥胖者）完成了两项基于食物的去/不去任务（一项是高热量食物，另一项是低热量食物作为不去刺激），一次是在ERP数据采集期间，一次是在fMRI数据采集期间。测试后，向参与者提供自由称重的食物自助餐。参与者还使用自动自我管理24小时饮食回忆（ASA 24）系统记录了他们四天的食物摄入量。个体招募更多的抑制控制时，对高热量的食物相比，低热量的食物，虽然这种效果是更一致的N2比P3或功能磁共振成像评估。BMI状态不影响食物相关的抑制控制。由N2振幅测量的较大抑制反应与ASA 24食物摄入量增加有关; P3振幅和fMRI感兴趣区域活动不能预测ASA 24摄入量;两种方法都不能预测自助餐的食物摄入量。ERP和功能磁共振成像测量显示类似的神经反应的食物，虽然N2振幅可能在检测食物类型之间的差异和预测自我报告的食物摄入量更敏感。
Obesity and maintaining a healthy diet have important implications for physical and mental health. One factor that may influence diet and obesity is inhibitory control. We tested how N2 and P3 amplitude, event-related potential (ERP) components that reflect inhibitory control, and functional magnetic resonance imaging (fMRI) activity in brain regions associated with inhibitory control differed toward high-and low-calorie food stimuli across BMI status. We also assessed the relationship between neural indices of food-related inhibitory control and laboratory and daily food intake. Fifty-four individuals (17 normal-weight; 18 overweight; 19 individuals with obesity) completed two food-based go/no-go tasks (one with high-and one with low-calorie foods as no-go stimuli), once during ERP data acquisition and once during fMRI data acquisition. After testing, participants were presented with an ad libitum weighed food buffet. Participants also recorded their food intake using the Automated Self-Administered 24-hour Dietary Recall (ASA24) system across four days. Individuals recruited more inhibitory control when withholding responses towards high-compared to low-calorie foods, although this effect was more consistent for N2 than P3 or fMRI assessments. BMI status did not influence food-related inhibitory control. A larger inhibitory response as measured by N2 amplitude was related to increased ASA24 food intake; P3 amplitude and fMRI region of interest activity did not predict ASA24 intake; neither method predicted food intake from the buffet. ERP and fMRI measurements show similar neural responses to food, although N2 amplitude may be somewhat more sensitive in detecting differences between food types and predicting self-reports of food intake.