Amphidinolides B6 and B7, cytotoxic Macrolides from a symbiotic dinoflagellate Amphidinium species

Amphidinolides B6 and B7, cytotoxic Macrolides from a symbiotic dinoflagellate Amphidinium species
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DOI:
10.1021/np0703085
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发表时间:
2007-10-01
影响因子:
5.1
通讯作者:
Masuda, Atsunori
Masuda, Atsunori
中科院分区:
生物学2区
文献类型:
--
作者:
Oguchi, Keiko;Tsuda, Masashi;Masuda, Atsunori

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从海洋共生甲藻中分离得到两个26元大环内酯化合物B6(2)和B7(1),其结构经二维核磁共振数据的详细分析得到确证。1和2的相对构型和绝对构型是通过核磁共振数据和CD数据与已知的苯并烷内酯的比较来指认的。
Two 26-membered macrolides, amphidinolides B6 (2) and B7 (1), have been isolated from a marine symbiotic dinotlagellate Amphidinium sp., and the structures were elucidated on the basis of detailed analyses of 2D NMR data. The relative and absolute configurations for 1 and 2 were assigned by comparison of NMR data and CD data with those of known amphidinolides.