Absorbed dose estimation using LET dependence in glow curve of thermoluminescent phosphor Li3B7O12:Cu in therapeutic carbon beam
Absorbed dose estimation using LET dependence in glow curve of thermoluminescent phosphor Li3B7O12:Cu in therapeutic carbon beam
复制标题
利用治疗碳束中热释光磷光体 Li3B7O12:Cu 的辉光曲线中的 LET 依赖性估算吸收剂量
DOI：
10.1080/00223131.2016.1181010
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发表时间：
2016
影响因子：
1.2
通讯作者：
Kiyomitsu Shinsho
中科院分区：
文献类型：
--
作者：
Weishan Chang;Yusuke Koba;Shigekazu Fukuda;Genichiro Wakabayashi;Hidetoshi Saitoh;Kiyomitsu Shinsho
提出了一种高温比(HTR)方法来修正热释光(TL)效率与线性能量转移(LET)的关系。为了实现基于荧光粉Li3B7O12：Cu的板条型热释光探测器(TLD)在重荷电粒子束上的应用，考虑了HTR方法。为了提高高温气冷堆的重现性，本文引入了慢升温速率法，使高温气冷堆的系数变化从10%-20%降低到8%。研究了Li_3B_7O_(12)：Cu的热释光效率、热释光效率和LET之间的关系，导出了热释光效率与热释光效率的函数关系，以求在没有LET信息的情况下测量吸收剂量。通过比较Li3B7O12：Cu和电离室估算的剂量，评估了HTR方法在治疗碳束中的可行性。高温气冷堆方法提高了碳束剂量估算的准确性，但仍有进一步提高的空间。随着高温气冷堆灵敏度的进一步提高，Li3B7O12：Cu在重荷粒子束中的应用有望实现。
A high temperature ratio (HTR) method has been proposed to correct the linear energy transfer (LET) dependence of thermoluminescent (TL) efficiency. To realize the use of the slab-type thermoluminescence detector (TLD) that based on the phosphor Li3B7O12:Cu for heavy charged particle beam, the HTR method has been considered. To improve the reproducibility of HTR, the slow heating rate method is introduced in this report and the coefficient variations of HTR decreased from 10%–20% to 8%. The relation between TL-efficiency, HTR, and LET for Li3B7O12:Cu was manifested and the TL-efficiency as a function of HTR was derived in an attempt to measure the absorbed dose without LET information. The feasibility of the HTR method in therapeutic carbon beams was evaluated by comparing the dose estimated by Li3B7O12:Cu and by an ionization chamber. The accuracy of dose estimation in carbon beams was improved by using the HTR method, but there is room for further improvement. The use of Li3B7O12:Cu in heavy charged particle beams can be materialized with further improvement of HTR sensitivity.