"Double depression": two-year follow-up.
"Double depression": two-year follow-up.
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“双重抑郁症”：两年随访。
DOI：
10.1176/ajp.140.6.689
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
Klerman,GL
中科院分区：
文献类型：
--
作者：
Keller,MB;Lavori,PW;Endicott,J;Coryell,W;Klerman,GL
对 3×16 名重度抑郁症患者进行了 6 个月至 2 年的随访，其中 80 名 (25%) 患有至少持续 2 年的慢性轻度抑郁症。慢性轻度抑郁症降低了已知的重度抑郁症恢复和复发预测因素的明显效果，并预测了慢性抑郁症的非常有害的病程。此外，患者从重度抑郁症恢复后继续患有慢性轻度抑郁症的时间越长，复发为另一次重度抑郁症抢先从慢性抑郁症恢复的可能性就越大。
Of 3 16 patients with a major depressive disorder who were followed for between 6 months and 2 years, 80 (25%) had a preexisting chronic minor depression of at least 2 years’ duration. The chronic minor depression reduced the apparent effect of the known predictors of recovery and relapse from the major depressive disorder and predicted a very pernicious course for the chronic depression. Furthermore, the longer the patient continued to suffer from a chronic minor depression after recovering from the major depression, the greater the probability that relapse into another major depression would preempt recovery from the chronic depression.