Roles of TRAF molecules in B lymphocyte function

Roles of TRAF molecules in B lymphocyte function
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DOI:
10.1016/j.cytogfr.2008.04.002
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发表时间:
2008-06-01
影响因子:
13
通讯作者:
Bishop, Gail A.
Bishop, Gail A.
中科院分区:
医学2区
文献类型:
--
作者:
Xie, Ping;Kraus, Zachary J.;Bishop, Gail A.

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肿瘤坏死因子受体相关因子(TRAFs)在B淋巴细胞功能的调节中发挥着多种有趣而重要的作用。它们既是细胞质调节分子,又是参与先天性和适应性不道德免疫反应的受体的信号传导器。在这篇简短的综述中,我们强调了TRAF分子在B淋巴细胞功能中的不同作用的知识现状。(c)2008爱思唯尔有限公司保留所有权利。
Tumor necrosis factor receptor associated factors (TRAFs) play a variety of interesting and important roles in the regulation of B lymphocyte function. They act both as cytoplasmic regulatory molecules, and as signal transducers for receptors involved in both innate and adaptive Immoral immune responses. In this brief review, we highlight the current state of knowledge of the diverse roles of TRAF molecules in the functions of B lymphocytes. (c) 2008 Elsevier Ltd. All rights reserved.