Noninvasive brain stimulation in psychiatric disorders: a primer.
Noninvasive brain stimulation in psychiatric disorders: a primer.
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DOI：
10.1590/1516-4446-2017-0018
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发表时间：
2019-01
期刊：
影响因子：
--
通讯作者：
Valiengo L
中科院分区：
文献类型：
--
作者：
Brunoni AR;Sampaio-Junior B;Moffa AH;Aparício LV;Gordon P;Klein I;Rios RM;Razza LB;Loo C;Padberg F;Valiengo L
非侵入性脑刺激技术，如经颅直流电刺激和重复经颅磁刺激，正越来越多地被用于治疗精神障碍，特别是重度抑郁症。这一全面审查的目的是总结该领域的主要进展、局限性和前景。我们在PubMed和其他数据库中搜索从最初到2017年7月的文章，特别是系统综述和荟萃分析，评估NIB在精神障碍中的使用。我们对NIBs的作用机制、安全性、耐受性、有效性和相关的临床参数进行了综述。重复TMS已经是一种治疗抑郁症的既定技术，从理论上讲，有进一步的方法学发展空间，以实现高端治疗干预。相比之下，tDCSs是一种技术上更简单的方法，因此有可能适合更广泛的临床应用。然而，其抗抑郁疗效的证据并不可靠，最近的一项研究发现，tdcs不如抗抑郁药物治疗。使用rTMS治疗其他精神障碍的临床试验结果喜忧参半，而tdcs的使用还没有得到充分的评价。NIBS在治疗抑郁症方面取得了最有希望的结果。这些技术在安全性和耐受性方面都很出色，尽管它们的有效性仍然需要改进。
Noninvasive brain stimulation (NIBS) techniques, such as transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS), are increasingly being used to treat mental disorders, particularly major depression. The aim of this comprehensive review is to summarize the main advances, limitations, and perspectives of the field. We searched PubMed and other databases from inception to July 2017 for articles, particularly systematic reviews and meta-analyses, evaluating the use of NIBS in psychiatric disorders. We reviewed the mechanisms of action, safety, tolerability, efficacy, and relevant clinical parameters of NIBS. Repetitive TMS is already an established technique for the treatment of depression, and there is theoretically room for further methodological development towards a high-end therapeutic intervention. In contrast, tDCS is a technically easier method and therefore potentially suitable for wider clinical use. However the evidence of its antidepressant efficacy is less sound, and a recent study found tDCS to be inferior to antidepressant pharmacotherapy. Clinical trials using rTMS for other mental disorders produced mixed findings, whereas tDCS use has not been sufficiently appraised. The most promising results of NIBS have been obtained for depression. These techniques excel in safety and tolerability, although their efficacy still warrants improvement.
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影响因子：
7.7
作者：
Brunoni, Andre Russowsky;Nitsche, Michael A.;Bolognini, Nadia;Bikson, Marom;Wagner, Tim;Merabet, Lotfi;Edwards, Dylan J.;Valero-Cabre, Antoni;Rotenberg, Alexander;Pascual-Leone, Alvaro;Ferrucci, Roberta;Priori, Alberto;Boggio, Paulo Sergio;Fregni, Felipe
通讯作者：
Fregni, Felipe
DOI：
10.4088/jcp.08m04638blu
发表时间：
2010-08
期刊：
The Journal of clinical psychiatry
影响因子：
--
作者：
Boggio PS;Rocha M;Oliveira MO;Fecteau S;Cohen RB;Campanhã C;Ferreira-Santos E;Meleiro A;Corchs F;Zaghi S;Pascual-Leone A;Fregni F
通讯作者：
Fregni F
影响因子：
4.8
作者：
Batista, Edson Kruger;Klauss, Jaisa;Nakamura-Palacios, Ester Miyuki
通讯作者：
Nakamura-Palacios, Ester Miyuki
影响因子：
7.7
作者：
Bakker, Nathan;Shahab, Saba;Downar, Jonathan
通讯作者：
Downar, Jonathan
影响因子：
7.4
作者：
D'Urso, Giordano;Brunoni, Andre R.;Mantovani, Antonio
通讯作者：
Mantovani, Antonio