Raised serum levels of IgE in infectious mononucleosis.
Raised serum levels of IgE in infectious mononucleosis.
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传染性单核细胞增多症血清 IgE 水平升高。
DOI：
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发表时间：
1972
影响因子：
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通讯作者：
Å. Espmark
中科院分区：
文献类型：
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作者：
F. Nordbring;S. Gunnar;O. Johansson;Å. Espmark
用放射免疫吸附技术测定了24例传染性单核细胞增多症患者血清中免疫球蛋白(Ig)E的浓度。4例患者在发病7-10天后血清中出现极高水平。这些水平与迄今仅在患有过敏性疾病或蠕虫感染的患者中看到的水平一样高。高浓度迅速下降。其余患者的水平正常、同样降低或低于正常。免疫球蛋白M也有类似的趋势，证实了以前的结果。少数患者的免疫球蛋白、免疫球蛋白A和免疫球蛋白D升高。注意到的免疫球蛋白变化可能被解释为传染性单核细胞增多症的强烈免疫反应特征的标志。
AbstractThe concentration of immunoglobulin (Ig) E was determined by a radioimmunosorbent technique in sera of 24 patients with infectious mononucleosis. Four patients had extremely high levels in sera obtained 7–10 days after the onset of the disease. These levels were as high as those hitherto seen only in patients with allergic diseases or worm infestations. The high concentrations decreased rapidly. The remaining patients had normal, likewise decreasing, or subnormal levels. A similar trend for IgM was observed, confirming previous results. IgG, IgA and IgD were elevated in a few patients. The immunoglobulin changes noted may be interpreted as a sign of the intense immune response characteristic of infectious mononucleosis.