The effect of femoral lengthening on knee articular cartilage: the role of apparatus extension across the joint.
The effect of femoral lengthening on knee articular cartilage: the role of apparatus extension across the joint.
复制标题
股骨延长对膝关节软骨的影响：器械跨关节延伸的作用。
DOI：
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发表时间：
1996
期刊：
影响因子：
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通讯作者：
M. Torosian
中科院分区：
文献类型：
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作者：
D. Stanitski;K. Rossman;M. Torosian
关节活动丧失是肢体延长的常见并发症，尽管有较新的增量骨延长方法。前导犬的研究表明，30%的股骨延长会导致可复制的膝关节软骨损伤，表现为软骨物质的明显丢失或纤颤。本研究旨在探讨器械伸展至胫骨对膝关节的保护作用。四只狗接受了改良的Ilizarov器械应用于股骨和胫骨，膝部有同轴铰链。截骨后，每天延长30%，每次0.75 mm，每次3次。延长完成后，取实验性和对侧膝关节，进行大体评估、脱钙、矢状切片和藏红花-O染色。所有对照关节的组织学检查均正常。所有实验关节都显示蛋白多糖染色减少，没有纤颤或坏死的证据。这些发现表明，通过避免关节受压，胫骨装置具有保护作用。
Loss of joint motion is a common complication of limb lengthening despite newer methods of incremental bone elongation. A pilot canine study has demonstrated that 30% femoral lengthening causes reproducible knee cartilage injury manifest by frank loss of cartilage substance or fibrillation. This study was undertaken to examine the potential of knee joint protection by apparatus extension to the tibia. Four dogs underwent application of a modified Ilizarov apparatus to the femur and tibia with coaxial hinges at the knee. After osteotomy, 30% lengthening was undertaken at 0.75 mm daily in three increments. At the completion of lengthening, experimental and contralateral knee joints were harvested, assessed grossly, decalcified, sagittally sectioned, and stained with safranin-O. All control joints were normal histologically. All experimental joints demonstrated a decrease in proteoglycan staining without evidence of fibrillation or necrosis. These findings suggest a protective effect of the tibial apparatus by avoiding joint compression.