Projections of the nuclei of the periaqueductal gray matter in the cat
Projections of the nuclei of the periaqueductal gray matter in the cat
复制标题
猫导水管周围灰质核的投影
DOI：
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发表时间：
1973
期刊：
影响因子：
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通讯作者：
B. Hamilton
中科院分区：
文献类型：
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作者：
B. Hamilton
为了获得更多支持猫导水管周围灰质（PAG）三核分裂理论的证据，对每个核的投射系统进行了研究。将直流电损伤立体定位在 PAG 的三个核中，并通过还原银浸渍技术对所得变性纤维进行染色。来自内侧核病变的退化轴突在腹侧以放射状方式追踪到被盖，并在嘴侧追踪到福雷尔区和腹侧被盖区。下降纤维被追踪到其终止于背侧被盖核。背核损伤不会导致辐射或下降纤维变性，但 PAG 内运行的一束变性纤维可以追踪到中脑-间脑交界处的水平。这里，轴突终止于顶盖前区域和外侧缰核。上述两个核病变的变性模式完全是同侧，而第三个核（外侧核）则主要是同侧。从它开始，所有的上升纤维都是同侧的，但是顶盖和被盖的重辐射纤维确实稍微延伸到了对侧。变性的大轴突束在 PAG 内向头侧延伸至间脑水平，并分为许多束并终止于脑室周围灰质、下丘脑后部和许多丘脑核。每个核投射不同的证据支持 PAG 三核分裂理论。
To obtain more evidence in support of the theory of tri‐nuclear division of the periaqueductal gray matter (PAG) in the cat, the projection systems of each of the nuclei were investigated. Direct current lesions were stereotaxically placed in the three nuclei of the PAG and the resulting fibers of degeneration were stained by reduced silver impregnation techniques. Degenerating axons from the lesion in the nucleus medialis were traced ventrally to the tegmentum in a radiating pattern and rostrally to the fields of Forel and the ventral tegmental area. Descending fibers were traced to their termination in the dorsal tegemental nucleus. Lesions in the nucleus dorsalis resulted in no radiating or descending fibers of degeneration, but a bundle of degenerating fibers running within the PAG could be followed to the level of the mesencephalic‐diencephalic junction. Here the axons terminated in the pretectal area and the lateral habenular nucleus. The pattern of degeneration was completely ipsilateral for the two nuclear lesions described above and predominately ipsilateral for the third nucleus, the lateralis. From it, all the ascending fibers were ipsilateral, but the heavy radiating fibers to the tectum and tegmentum did extend somewhat to the contralateral side. The large bundle of axons of degeneration ran rostrally within the PAG to diencephalic levels and divided into numerous fasciculi and terminated in the periventricular gray, the posterior hypothalamus and numerous thalamic nuclei. The evidence that each nucleus projects differently supports the theory of tri‐nuclear division of the PAG.