Response and habituation of the human amygdala during visual processing of facial expression
Response and habituation of the human amygdala during visual processing of facial expression
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DOI：
10.1016/s0896-6273(00)80219-6
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发表时间：
1996-11-01
期刊：
影响因子：
16.2
通讯作者：
Rosen, BR
中科院分区：
文献类型：
--
作者：
Breiter, HC;Etcoff, NL;Rosen, BR
我们使用功能性磁共振成像（fMRI）测量了人类志愿者在快速视觉呈现恐惧，快乐和中性面孔时的杏仁核活动。第一个实验涉及一个固定的顺序内和跨运行的条件，而第二个使用一个完全平衡的顺序，除了一个低水平的基线简单的视觉刺激。在这两个实验中，杏仁核优先被激活，以回应恐惧和中立的面孔。在平衡实验中，杏仁核也优先对快乐的面孔而不是中性面孔做出反应，这表明对情绪化的刺激可能有一种普遍的反应。快速习惯化效应在两个实验中都很突出。因此，人类的杏仁核会优先对情绪化的面孔做出反应，并迅速适应它们。
We measured amygdala activity in human volunteers during rapid visual presentations of fearful, happy, and neutral faces using functional magnetic resonance imaging (fMRI). The first experiment involved a fixed order of conditions both within and across runs, while the second one used a fully counterbalanced order in addition to a low level baseline of simple visual stimuli. In both experiments, the amygdala was preferentially activated in response to fearful versus neutral faces. In the counterbalanced experiment, the amygdala also responded preferentially to happy versus neutral faces, suggesting a possible generalized response to emotionally valenced stimuli. Rapid habituation effects were prominent in both experiments. Thus, the human amygdala responds preferentially to emotionally valenced faces and rapidly habituates to them.