Inherited dental anomalies: a review and prospects for the future role of clinicians.
Inherited dental anomalies: a review and prospects for the future role of clinicians.
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DOI：
10.1080/19424396.2007.12221232
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发表时间：
2007-05
期刊：
影响因子：
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通讯作者：
T. Pemberton;Gustavo Mendoza;J. Gee;P. Patel
中科院分区：
文献类型：
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作者：
T. Pemberton;Gustavo Mendoza;J. Gee;P. Patel
遗传性牙齿异常，如缺牙、多生牙、釉质缺损和牙间隙在大多数人群中很明显。虽然许多这些条件的治疗方案不断改善，仍有很多要了解他们的病因和病理生理学。在这篇综述中，作者希望通过合作研究寻求牙齿异常的潜在遗传原因并将这些疾病的患者介绍给人类遗传学家，从而使牙科专业人员热衷于帮助人类遗传学家。
Inherited dental anomalies such as hypodontia, supernumerary teeth, enamel defects, and diastema are evident in large segments of most populations. Although treatment options for many of these conditions are ever improving, much remains to be understood about their etiology and pathophysiology. In this review, the authors hope to enthuse dental professionals into aiding the human geneticist by collaborating in studies seeking the underlying genetic cause of dental anomalies and referring patients presenting these conditions to the human geneticist.