A Monte Carlo dose calculation tool for radiotherapy treatment planning
A Monte Carlo dose calculation tool for radiotherapy treatment planning
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DOI：
10.1088/0031-9155/47/10/305
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发表时间：
2002-05-21
影响因子：
3.5
通讯作者：
Brain, S
中科院分区：
文献类型：
--
作者：
Ma, CM;Li, JS;Brain, S
已经开发了用于放射治疗计划（RTP）剂量计算的蒙特卡洛用户代码。 McDose设计为适合适应主机RTP系统的剂量计算模块。 McDose可用于常规光子/电子束计算和强度调制放射疗法（IMRT）治疗计划。 McDose使用多种源模型来重建处理光束相空间。基于在调试过程中获得的蒙特卡洛模拟或测量的光束数据，通过自动化过程调整源模型参数。梁修饰符（例如下巴）。物理和动态楔子。补偿器。通过McDose以及由CT数据构建的3D直线患者几何模型，通过McDose模拟块，电子切口和推注。使用McDose计算得出的剂量分布与使用不同的梁设置和梁修饰符计算出的EGS4/dosxyz代码计算的剂量分布非常吻合。通过两种代码计算的分层肺或分层骨幻像的异质性校正因子与测量数据一致，至1％以内。研究了能量切割对粒子运输的影响。与dosxyz相比，麦克多斯（McDose）实施了差异技术，以达到10-30的加速系数。
A Monte Carlo user code, MCDOSE, has been developed for radiotherapy treatment planning (RTP) dose calculations. MCDOSE is designed as a dose calculation module suitable for adaptation to host RTP systems. MCDOSE can be used for both conventional photon/electron beam calculation and intensity modulated radiotherapy (IMRT) treatment planning. MCDOSE uses a multiple-source model to reconstruct the treatment beam phase space. Based on Monte Carlo simulated or measured beam data acquired during commissioning, source-model parameters are adjusted through an automated procedure. Beam modifiers such as jaws. physical and dynamic wedges. compensators. blocks, electron cut-outs and bolus are simulated by MCDOSE together with a 3D rectilinear patient geometry model built from CT data. Dose distributions calculated using MCDOSE agreed well with those calculated by the EGS4/DOSXYZ code using different beam set-ups and beam modifiers. Heterogeneity correction factors for layered-lung or layered-bone phantoms as calculated by both codes were consistent with measured data to within 1%. The effect of energy cut-offs for particle transport was investigated. Variance reduction techniques were implemented in MCDOSE to achieve a speedup factor of 10-30 compared to DOSXYZ.