Real time bio mechanical characterization of DNA damage under therapeutic radiation beams
Real time bio mechanical characterization of DNA damage under therapeutic radiation beams
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治疗辐射束下 DNA 损伤的实时生物力学表征
DOI:
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发表时间:
2013
期刊:
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通讯作者:
D. Collard
中科院分区:
文献类型:
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作者:
G. Perret;T. Lacornerie;M. Kumemura;N. Lafitte;H. Guillou;L. Jalabert;E. Lartigau;T. Fujii;F. Cleri;H. Fujita;D. Collard
We report the first real-time biomechanical measurement of DNA bundle degradation in solution when exposed to a therapeutic radiation beam. The Silicon Nano Tweezers and their microfluidic endure the harsh environment of radiation beams and still retain molecular-level accuracy. This result paves the way for both fundamental and clinical studies of DNA degradation under radiation for improved tumor treatment.