Real time bio mechanical characterization of DNA damage under therapeutic radiation beams

Real time bio mechanical characterization of DNA damage under therapeutic radiation beams
复制标题

治疗辐射束下 DNA 损伤的实时生物力学表征

DOI:
--
复制
发表时间:
2013
期刊:
--
影响因子:
--
通讯作者:
D. Collard
D. Collard
中科院分区:
--
文献类型:
--
作者:
G. Perret;T. Lacornerie;M. Kumemura;N. Lafitte;H. Guillou;L. Jalabert;E. Lartigau;T. Fujii;F. Cleri;H. Fujita;D. Collard

文献摘要

被引文献

相似文献

我们报告的第一个实时生物力学测量DNA束降解溶液中暴露于治疗辐射束。硅纳米镊子及其微流体能够承受辐射束的恶劣环境,仍然保持分子级的精度。这一结果为辐射下DNA降解的基础和临床研究铺平了道路,以改善肿瘤治疗。
We report the first real-time biomechanical measurement of DNA bundle degradation in solution when exposed to a therapeutic radiation beam. The Silicon Nano Tweezers and their microfluidic endure the harsh environment of radiation beams and still retain molecular-level accuracy. This result paves the way for both fundamental and clinical studies of DNA degradation under radiation for improved tumor treatment.