Types and Forms of Tourism
Types and Forms of Tourism
复制标题
旅游的类型和形式
DOI：
10.1089/jmf.2023.0203
复制
发表时间：
2008
影响因子：
2.4
通讯作者：
C. Tureac
中科院分区：
文献类型：
--
作者：
A. Turtureanu;C. Tureac
一些饮食模式与炎症有关，而另一些则降低炎症，改善健康。然而，许多人不能遵循完整、健康的饮食。因此，这项研究的目的是确定与慢性炎症和死亡率相关的特定食物。这项研究使用了来自NHLBI生物标本和数据存储库信息协调中心的多种族动脉粥样硬化研究(MESA)研究材料。根据西方饮食中可获得的感知，选择了三种植物性和三种动物性台地食品类别。被评估的食物类别是鳄梨、火腿、香肠、鸡蛋、蔬菜和西兰花。炎症标志物包括白介素6(IL-6)、纤维蛋白原抗原、C反应蛋白、D-二聚体、白介素2、基质金属蛋白酶3、坏死因子-a可溶性受体、氧化型低密度脂蛋白(OxLDL)和总同型半胱氨酸。主要结果是食物和炎症标记物与全因死亡率之间的多变量关联。单因素分析显示，除oxLDL外，所有炎症标志物均与死亡率相关。IL-6和D-二聚体的作用最大。在单变量分析中，西兰花的类别与较低的炎症和较低的死亡几率具有最一致的相关性。在使用IL-6和D-二聚体的多变量模型中，与不食用西兰花相比，食用西兰花的低和高与较低的死亡率相关。食用MESA定义的食物类别“花椰菜”(即花椰菜、卷心菜、花椰菜、球芽甘蓝、酸菜和泡菜)与较低的炎症和较低的死亡几率有关。这些发现应该在随机对照试验中得到验证，该试验测试一种“食物就是药物”的方法，以确定这些食物中的哪些可能具有治疗慢性炎症的草药治疗潜力。
Some dietary patterns are associated with inflammation, while others lower inflammation and improve health. However, many people cannot follow a complete, healthy diet. Therefore, this study's aim was to identify specific foods associated chronic inflammation and mortality. The study used Multi-Ethnic Study of Atherosclerosis (MESA) research materials from the NHLBI Biologic Specimen and Data Repository Information Coordinating Center. Three plant-based and three animal-based MESA food categories were chosen based on perceived availability in the western diet. The assessed food categories were avocado, ham, sausage, eggs, greens, and broccoli. Inflammatory markers assessed were interleukin-6 (IL-6), fibrinogen antigen, C-reactive protein, D-Dimer, interleukin-2, matrix metalloproteinase 3, necrosis factor-a soluble receptors, oxidized LDL (oxLDL), and total homocysteine. The primary outcome was the multivariable association of foods and inflammatory markers with all-cause mortality. All inflammatory makers, except oxLDL, were associated with mortality in univariate analysis. The effect was largest with IL-6 and D-dimer. The category of broccoli had the most consistent association in univariate analyses with lower inflammation and lower mortality odds. Low and high broccoli consumption versus no consumption were associated with lower mortality odds in the multivariable models with IL-6 and D-dimer. Consumption of the MESA-defined food category “broccoli” (i.e., broccoli, cabbage, cauliflower, brussels sprouts, sauerkraut, and kimchee) was associated with lower inflammation and lower mortality odds. These findings should be validated in randomized controlled trials testing a “food is medicine” approach to identify which, if any, of these foods may have potential as an herbal therapeutic for chronic inflammation.