Association between autonomic disorders and subclinical atherosclerosis
Association between autonomic disorders and subclinical atherosclerosis
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DOI：
10.1016/j.hipert.2020.03.001
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发表时间：
2020-07-01
影响因子：
0.6
通讯作者：
Bonaccorsi, H. A.
中科院分区：
文献类型：
--
作者：
Mendo, D. S.;Gonzalez, S. A.;Bonaccorsi, H. A.
简介和目的：长期以来，交感和副交感神经系统的改变被认为是动脉粥样硬化发生和延续的前兆。本研究的目的是确定颈动脉粥样硬化的存在与心率变异性的降低之间是否存在关联。方法：采用前瞻性病例对照设计，对54例患者的心率变异性及有无颈动脉粥样硬化进行调查，根据有无颈动脉粥样硬化分为2组。分析了高频段、低频段、副交感神经自主平衡和总频谱频段的频率（谱）域心率变异性变量。结果：在连续无心血管疾病的54例患者中，26例（48%）出现亚临床颈动脉粥样硬化（ATE+）。在ATE+组中观察到心率变异性的降低，由低频（LF）谱(P
Introduction and objectives: Alterations of the sympathetic and parasympathetic nervous system have been proposed as precursors of the genesis and perpetuation of atherosclerosis for a long time. The objective of this study is to determine if there is an association between the presence of carotid atherosclerosis and the reduction in heart rate variability.Methods: Using a prospective case-control design, the heart rate variability and the presence of carotid atherosclerosis was investigated in 54 patients, divided into 2 groups according to the presence or absence of carotid atherosclerosis. An analysis was made of the heart rate variability variables of the frequency (spectral) domain in high frequency band, low frequency band, parasympathetic autonomic balance, and the total spectral band.Results: Of the 54 individuals evaluated without previous cardiovascular disease consecutively, 26 of them (48%) presented with subclinical carotid atherosclerosis (ATE+). A reduction in heart rate variability was observed in the ATE+ group represented by the low frequency (LF) spectrum (P