Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study: Implications for large-scale biomonitoring studies
Bisphenol-A and phthalates contamination of urine samples by catheters in the Elfe pilot study: Implications for large-scale biomonitoring studies
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DOI:
10.1016/j.envres.2011.05.018
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发表时间:
2011-08-01
影响因子:
8.3
通讯作者:
Leridon, Henri
中科院分区:
文献类型:
--
作者:
Vandentorren, Stephanie;Zeman, Florence;Leridon, Henri
Exposure to phthalates and Bisphenol A could cause developmental and reproductive toxicity. This study provides a first assessment of these exposures for more than 250 French pregnant women. The median concentrations of total and free Bisphenol A in urine were similar to those in other studies except the highest concentrations (5% of women had total and free Bisphenol A > 50 mu g/L). Our study highlights high levels of Di-(2-ethylhexyl)-phthalate metabolites in pregnant women, suggesting recent exposure, probably in hospital. Differences between types of delivery (caesarean vs. natural) support this hypothesis. This is a significant implication for large-scale biomonitoring studies among this population. (C) 2011 Elsevier Inc. All rights reserved.