Factors predicting sensory and motor recovery after the repair of upper limb peripheral nerve injuries.
Factors predicting sensory and motor recovery after the repair of upper limb peripheral nerve injuries.
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DOI：
10.4103/1673-5374.130094
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发表时间：
2014-03-15
影响因子：
6.1
通讯作者：
Zhu J
中科院分区：
文献类型：
--
作者：
He B;Zhu Z;Zhu Q;Zhou X;Zheng C;Li P;Zhu S;Liu X;Zhu J
目的探讨上肢周围神经损伤修复后感觉和运动功能恢复的相关因素。在线PubMed数据库检索了发表日期在1990年1月1日至2011年2月16日之间的描述人类正中神经、尺神经、桡神经和指神经损伤修复后结果的英文文章。选择以下类型的文章：(1)以英文发表的描述正中神经、尺神经、桡神经和指神经损伤修复的临床试验；(2)患者年龄、损伤机制、损伤神经、损伤部位、缺损长度、修复时间、修复方式、修复材料等信息充分的研究。采用SPSS 13.0软件进行单因素和多因素logistic回归分析，探讨与结果相关的患者和干预因素。用Mackinnon-Dellon量表评估感觉功能，用手肌测试评估运动功能。运动恢复满意定义为M4或M5级，感觉恢复满意定义为S3+或S4级。本研究共纳入71篇文章。单因素和多因素logistic回归分析显示，修复时间、修复材料、神经损伤程度是神经损伤修复后预后的独立预测因素（P < 0.05），神经损伤程度是影响优良率的主要因素。周围神经损伤修复后预后的预测因素包括年龄、性别、修复时间、修复材料、神经损伤、缺损长度、随访时间等。
To investigate the factors associated with sensory and motor recovery after the repair of upper limb peripheral nerve injuries. The online PubMed database was searched for English articles describing outcomes after the repair of median, ulnar, radial, and digital nerve injuries in humans with a publication date between 1 January 1990 and 16 February 2011. The following types of article were selected: (1) clinical trials describing the repair of median, ulnar, radial, and digital nerve injuries published in English; and (2) studies that reported sufficient patient information, including age, mechanism of injury, nerve injured, injury location, defect length, repair time, repair method, and repair materials. SPSS 13.0 software was used to perform univariate and multivariate logistic regression analyses and to investigate the patient and intervention factors associated with outcomes. Sensory function was assessed using the Mackinnon-Dellon scale and motor function was assessed using the manual muscle test. Satisfactory motor recovery was defined as grade M4 or M5, and satisfactory sensory recovery was defined as grade S3+ or S4. Seventy-one articles were included in this study. Univariate and multivariate logistic regression analyses showed that repair time, repair materials, and nerve injured were independent predictors of outcome after the repair of nerve injuries (P < 0.05), and that the nerve injured was the main factor affecting the rate of good to excellent recovery. Predictors of outcome after the repair of peripheral nerve injuries include age, gender, repair time, repair materials, nerve injured, defect length, and duration of follow-up.